5-Fluoro-2-methylphenyl isocyanate
5-Fluoro-2-methylphenyl isocyanate (CAS: 67191-93-9, Formula: C7H6FNO, Molar Mass: 151.14) is a fluorinated aromatic isocyanate. It serves as a valuable building block in organic synthesis, particularly for introducing the 5-fluoro-2-methylphenylcarbamoyl moiety into various molecules. Its reactivity makes it useful in the preparation of diverse chemical compounds for research and development.
Organic Synthesis Intermediate
This compound is extensively employed as an intermediate in the synthesis of complex organic molecules. Its isocyanate group readily reacts with nucleophiles like alcohols, amines, and thiols to form carbamates, ureas, and thiocarbamates, respectively.
Pharmaceutical Research
As a fluorinated building block, it finds utility in the development of novel pharmaceutical agents. The incorporation of fluorine can significantly alter the pharmacokinetic and pharmacodynamic properties of drug candidates.
Agrochemical Development
The unique structural features of 5-Fluoro-2-methylphenyl isocyanate can be leveraged in the design and synthesis of new agrochemical compounds, potentially leading to improved efficacy or novel modes of action.
Material Science
Isocyanates are fundamental in polymer chemistry. This specific fluorinated derivative may be explored for the creation of specialty polymers or functional materials with tailored properties, such as altered thermal stability or surface characteristics.
| Molecular weight | 151.14 |
|---|---|
| Linear formula | FC6H3(CH3)NCO |
| Assay | 98% |
| Boiling point | 186 °C(lit.) |
| Density | 1.176 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.515(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 69 °C / 156.2 °F |
| Transport (UN / ADR) | UN 2206 6.1/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-2-methylphenyl isocyanate used for?
+
5-Fluoro-2-methylphenyl isocyanate is primarily used as a versatile intermediate in organic synthesis, particularly for introducing the 5-fluoro-2-methylphenylcarbamoyl group into molecules for pharmaceutical, agrochemical, and material science research and development.
What are the CAS number and chemical formula for 5-Fluoro-2-methylphenyl isocyanate?
+
The CAS number for 5-Fluoro-2-methylphenyl isocyanate is 67191-93-9, and its chemical formula is C7H6FNO.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 5-Fluoro-2-methylphenyl isocyanate with a purity of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade; it is supplied for research and laboratory use.
How should 5-Fluoro-2-methylphenyl isocyanate be handled safely?
+
5-Fluoro-2-methylphenyl isocyanate is a Warning substance, causing harm if swallowed (H302), in contact with skin (H312), or inhaled (H332), and causes skin (H315), eye (H319), and respiratory irritation (H335). It requires appropriate personal protective equipment, including eyeshields, faceshields, gloves, and suitable respiratory protection such as a full-face respirator or an ABEK filter.
How is 5-Fluoro-2-methylphenyl isocyanate packed and shipped?
+
Tech Serve Solutions, as a specialist global supplier and exporter, ensures that 5-Fluoro-2-methylphenyl isocyanate is appropriately packed and shipped in compliance with all relevant regulations for hazardous materials.
How can I request a quote or sample of 5-Fluoro-2-methylphenyl isocyanate?
+
To request a quote or a sample of 5-Fluoro-2-methylphenyl isocyanate, please contact our sales team through the provided channels on the Tech Serve Solutions website.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis