5-Fluoro-2-methylbenzenesulfonyl chloride
5-Fluoro-2-methylbenzenesulfonyl chloride (CAS: 445-05-6), with the chemical formula FC6H3(CH3)SO2Cl, is a key organic intermediate. Possessing a molecular weight of 208.64 g/mol, this fluorinated aromatic sulfonyl chloride serves as a versatile building block in organic synthesis. It is commonly employed in the preparation of diverse chemical compounds, contributing essential fluorine and sulfonyl chloride functionalities for further chemical transformations.
Organic Synthesis Intermediate
Utilised as a building block for constructing complex organic molecules. Its sulfonyl chloride group readily reacts with nucleophiles, enabling the introduction of the 5-fluoro-2-methylbenzenesulfonyl moiety.
Pharmaceutical Research
Serves as a valuable reagent in the discovery and development of new pharmaceutical compounds. The incorporation of fluorinated aromatic rings can significantly influence the pharmacokinetic and pharmacodynamic properties of drug candidates.
Agrochemical Development
Employed in the synthesis of novel agrochemicals, where fluorinated compounds often exhibit enhanced biological activity and metabolic stability.
Material Science
Can be incorporated into the synthesis of specialized polymers and materials, leveraging the unique electronic and physical properties imparted by the fluorinated aromatic structure.
| Molecular weight | 208.64 |
|---|---|
| Linear formula | FC6H3(CH3)SO2Cl |
| Assay | 97% |
| Density | 1.423 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5355(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-2-methylbenzenesulfonyl chloride used for?
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5-Fluoro-2-methylbenzenesulfonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What are the CAS number and chemical formula for 5-Fluoro-2-methylbenzenesulfonyl chloride?
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The CAS number is 445-05-6, and the chemical formula is FC6H3(CH3)SO2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Fluoro-2-methylbenzenesulfonyl chloride with a minimum assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety concerns when handling 5-Fluoro-2-methylbenzenesulfonyl chloride?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, is essential. Handle only in a well-ventilated area.
How is 5-Fluoro-2-methylbenzenesulfonyl chloride packed, shipped, and exported?
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As a global supplier and exporter, Tech Serve Solutions ensures that 5-Fluoro-2-methylbenzenesulfonyl chloride is packed and shipped in compliance with all relevant international regulations for hazardous materials, including UN 3265, Class 8, Packing Group II.
How can I request a quote or sample of 5-Fluoro-2-methylbenzenesulfonyl chloride?
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To request a quote or a sample of 5-Fluoro-2-methylbenzenesulfonyl chloride, please contact our sales department through the website or by phone, providing your details and desired quantity.
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