5-Fluoro-2-methoxyphenylmagnesium bromide solution
5-Fluoro-2-methoxyphenylmagnesium bromide solution (CAS: 188132-02-7, FC<sub>6</sub>H<sub>3</sub>(OCH<sub>3</sub>)MgBr, MW: 229.33) is a crucial organometallic reagent. As a Grignard reagent, it is widely employed in organic synthesis for forming new carbon-carbon bonds. Its utility lies in introducing the 5-fluoro-2-methoxyphenyl moiety into various organic molecules, facilitating the construction of complex chemical structures, particularly in pharmaceutical and agrochemical research.
- IUPAC
- 3-Fluoro-6-methoxyphenylmagnesium bromide solution
Organic Synthesis Intermediate
Utilised in the synthesis of complex organic molecules, leveraging its Grignard reactivity to introduce the 5-fluoro-2-methoxyphenyl group. This is valuable in constructing pharmaceutical intermediates and advanced materials.
Pharmaceutical Research and Development
Serves as a building block in the discovery and development of new drug candidates. The fluoro-methoxy-phenyl structure is a motif found in various biologically active compounds.
Agrochemical Synthesis
Contributes to the creation of novel agrochemical compounds. The incorporation of fluorine and methoxy groups can influence the efficacy and properties of pesticides and herbicides.
Material Science
Can be employed in the synthesis of functional organic materials where specific electronic or structural properties are desired, stemming from the aryl halide precursor.
| Molecular weight | 229.33 |
|---|---|
| Linear formula | FC6H3(OCH3)MgBr |
| Boiling point | 65 °C |
| Density | 0.948 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-2-methoxyphenylmagnesium bromide solution used for?
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This solution is primarily used as an organometallic reagent in organic synthesis, particularly as a Grignard reagent for forming carbon-carbon bonds and introducing the 5-fluoro-2-methoxyphenyl group into various molecules.
What is the CAS number and formula for this product?
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The CAS number is 188132-02-7, and the linear formula is FC<sub>6</sub>H<sub>3</sub>(OCH<sub>3</sub>)MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a 0.5 M solution in THF. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade. Purity is typically that of a technical or research grade; please refer to the specific Certificate of Analysis for lot-specific details.
How should 5-Fluoro-2-methoxyphenylmagnesium bromide solution be handled?
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This product is highly flammable (H225) and can cause serious eye irritation (H319) and respiratory irritation (H335). It is also suspected of causing cancer (H351) and may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Store refrigerated at 2-8°C.
How is this chemical packed, shipped, and exported?
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This product is typically supplied in appropriate containers for air and sea transport, adhering to UN 2924, Class 8(3), PG II regulations. TSS exports globally, ensuring compliance with all international shipping and customs requirements.
How can I request a sample or quote?
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To request a sample or a quotation, please contact our sales team through the website or call us directly. Please specify the quantity and your delivery location.
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