5-Fluoro-2-methylaniline
5-Fluoro-2-methylaniline (CAS: 367-29-3), with the molecular formula FC6H3(CH3)NH2 and a molar mass of 125.14 g/mol, is an aromatic amine building block. This compound is a valuable intermediate in organic synthesis, particularly for the introduction of fluorinated aniline moieties into more complex molecules. It finds application in the development of pharmaceuticals, agrochemicals, and materials science, serving as a key component in the construction of diverse chemical entities.
- IUPAC
- 2-Amino-4-fluorotoluene,5-Fluoro-o-toluidine
- Synonyms
- 2-Amino-4-fluorotoluene5-Fluoro-o-toluidine

Pharmaceutical Intermediate
5-Fluoro-2-methylaniline serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs). Its fluorinated aromatic structure can influence the pharmacokinetic and pharmacodynamic properties of drug candidates.
Agrochemical Development
This compound is utilised in the research and development of novel agrochemicals, such as herbicides and pesticides. The incorporation of fluorine atoms can enhance the efficacy and metabolic stability of these agents.
Materials Science
In materials science, 5-Fluoro-2-methylaniline can be employed in the synthesis of specialty polymers and functional materials. The fluorine substituent can impart unique electronic or physical properties to the resulting materials.
Research and Development
As a versatile fluorinated building block, it is widely used in academic and industrial research laboratories for the exploration of new chemical reactions and the synthesis of novel organic compounds.
| Molecular weight | 125.14 |
|---|---|
| Linear formula | FC6H3(CH3)NH2 |
| Assay | 99% |
| Melting point | 38-40 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 90 °C / 194 °F |
| Transport (UN / ADR) | UN 1325 4.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-2-methylaniline used for?
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5-Fluoro-2-methylaniline is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. It is also employed in various research and development settings.
What is the CAS number and molecular formula for 5-Fluoro-2-methylaniline?
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The CAS number for 5-Fluoro-2-methylaniline is 367-29-3, and its molecular formula is FC6H3(CH3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Fluoro-2-methylaniline with a minimum assay of 99%. This product is intended for research and chemical synthesis purposes and is not represented as USP, EP, BP, or pharmaceutical grade.
What are the primary safety concerns when handling 5-Fluoro-2-methylaniline?
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5-Fluoro-2-methylaniline is classified with Warning signal word and poses hazards including H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used.
How is 5-Fluoro-2-methylaniline packed and shipped globally?
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Tech Serve Solutions offers 5-Fluoro-2-methylaniline in various pack sizes suitable for laboratory and industrial use. We are experienced exporters and ensure compliance with all relevant international shipping regulations for chemical products.
How can I request a quote or sample for 5-Fluoro-2-methylaniline?
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To request a quote or a sample of 5-Fluoro-2-methylaniline, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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