5-Fluoro-2-methoxyphenylboronic acid
5-Fluoro-2-methoxyphenylboronic acid (CAS: 179897-94-0, Formula: FC6H3(OCH3)B(OH)2) is a key organoborane reagent with a molecular weight of 169.95 g/mol. This disubstituted aryl boronic acid derivative is primarily employed as a reactant in Suzuki couplings and copper-catalyzed arylation reactions, facilitating the formation of new carbon-carbon and carbon-heteroatom bonds in organic synthesis.
- IUPAC
- 2-Methoxy-5-fluorophenylboronic acid
Suzuki Couplings
5-Fluoro-2-methoxyphenylboronic acid serves as a crucial building block in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. It enables the efficient synthesis of biaryl compounds and other complex organic molecules by forming a new C-C bond with aryl or vinyl halides/triflates.
Copper-Catalyzed Arylation
This boronic acid is utilized as a substrate in copper-catalyzed arylation reactions. It allows for the introduction of the 2-methoxy-5-fluorophenyl moiety onto various organic frameworks, expanding synthetic possibilities in medicinal chemistry and materials science.
Organic Synthesis Intermediate
As a versatile aryl boronic acid derivative, it finds application as an intermediate in the construction of diverse organic molecules. Its specific substitution pattern makes it valuable for targeted syntheses in research and development settings.
| Molecular weight | 169.95 |
|---|---|
| Linear formula | FC6H3(OCH3)B(OH)2 |
| Assay | ≥95% |
| Application | Reactant for:• Suzuki couplings1,2• Copper catalyzed arylation3 |
| Melting point | 144-153 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Fluoro-2-methoxyphenylboronic acid used for?
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5-Fluoro-2-methoxyphenylboronic acid is primarily used as a reactant in Suzuki couplings and copper-catalyzed arylation reactions, serving as a valuable intermediate in organic synthesis.
What is the CAS number and chemical formula for 5-Fluoro-2-methoxyphenylboronic acid?
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The CAS number is 179897-94-0 and the chemical formula is FC6H3(OCH3)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Fluoro-2-methoxyphenylboronic acid with an assay of ≥95%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations for this product?
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According to the data, this compound has a WGK rating of 3 in Germany. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used during handling to prevent exposure.
How is 5-Fluoro-2-methoxyphenylboronic acid packaged and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging details for 5-Fluoro-2-methoxyphenylboronic acid are available upon request. Please contact us for export information and shipping options.
How can I request a sample or quote for 5-Fluoro-2-methoxyphenylboronic acid?
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To request a sample or a quote for 5-Fluoro-2-methoxyphenylboronic acid, please use the contact form on our website or reach out to our sales team directly with your inquiry.
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