Nitrendipine

CAS 39562-70-4C18H20N2O6Biochemicals & Reagents

Nitrendipine (CAS 39562-70-4), a dihydropyridine derivative with the molecular formula C18H20N2O6 and a molecular weight of 360.36 g/mol, is a yellow to green powder. It is classified as a calcium channel modulator and is primarily utilised in research for its effects on voltage-gated ion channels. Its solubility profile indicates it is soluble in methanol and DMSO, but insoluble in water, making it suitable for specific laboratory applications.

IUPAC: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester
Synonyms: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester

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Nitrendipine (C18H20N2O6) — chemical structure, CAS 39562-70-4; Life Science, fine chemical supplied by Tech Serve Solutions

Application IndexBioactive Small MoleculesBiochemicals and ReagentsCalcium Channel ModulatorsCell BiologyCell Signaling EnzymesEnzymesInhibitorsand SubstratesInhibitors and Activators

01 /Applications

Calcium Channel Modulation Research

Nitrendipine serves as a valuable tool in scientific research for investigating the mechanisms of calcium channel activity. Its action as a modulator of voltage-gated calcium channels makes it instrumental in studies related to cellular signalling and physiological processes.

Cell Biology and Neuroscience Studies

As a bioactive small molecule, Nitrendipine is employed in cell biology research. It is particularly relevant in neuroscience, where it can be used to study the role of calcium channels in neuronal function and signalling pathways.

Biochemical and Reagent Applications

This compound functions as a biochemical reagent in laboratory settings. Researchers utilise it to probe enzyme activity, ion channel function, and other biological processes, contributing to a deeper understanding of complex biochemical pathways.

02 /Properties

Molecular weight	360.36
Empirical formula	C18H20N2O6
Assay	>95%
Form	powder
Colour	yellow to green
Solubility	methanol: soluble15 mg/mLDMSO: soluble17.5 mg/mLH2O: insoluble

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	1
Hazard codes (EU)	Xn
Risk statements (R)	20/21/22
Safety statements (S)	36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

39562-70-4

MDL number

MFCD00082255

05 /Additional specifications

Gene Information	human ... ADORA3(140), CACNG1(786), KCNH1(3756), TTR(7276)rat ... Adora1(29290), Adora2a(25369)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Nitrendipine used for?

Nitrendipine is used in scientific research, particularly in cell biology, neuroscience, and for studying calcium channel modulation. It is a valuable biochemical reagent for investigating voltage-gated ion channels and cellular signalling pathways.

What is the CAS number and formula for Nitrendipine?

The CAS number for Nitrendipine is 39562-70-4, and its molecular formula is C18H20N2O6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Nitrendipine with an assay of >95%. We do not represent this product as USP, BP, or EP grade.

What are the safety considerations when handling Nitrendipine?

Nitrendipine is classified as harmful if swallowed and harmful if inhaled (H302-H332). When handling, use a dust mask type N95 (US), eyeshields, and gloves. Store in a well-ventilated place.

How is Nitrendipine packed, shipped, and exported?

Nitrendipine is typically supplied as a powder. As a global supplier and exporter, Tech Serve Solutions adheres to all relevant regulations for the safe packing, shipping, and international export of chemical products.

How can I request a sample or quote for Nitrendipine?

To request a sample or a quote for Nitrendipine, please contact our sales department through the TSS website or via email, providing your contact details and the quantity required.