(E)-Guggulsterone

CAS 39025-24-6C21H28O2Biochemicals & Reagents

(E)-Guggulsterone (CAS: 39025-24-6), with the molecular formula C21H28O2 and a molecular weight of 312.45, is a bioactive small molecule. This white to off-white powder is utilized in biochemical research and cell biology studies. Its properties make it valuable for investigating cell signaling pathways, cholesterol metabolism, and enzyme inhibition, particularly in the context of multi-drug resistance mechanisms.

IUPAC: (17E)-Pregna-4,17(20)-diene-3,16-dione

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(E)-Guggulsterone (C21H28O2) — chemical structure, CAS 39025-24-6; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCell BiologyDrug Efflux PumpsEnzyme InhibitorsEnzyme Inhibitors by EnzymeEnzymesInhibitorsand SubstratesLipids in Cell Signaling

01 /Applications

Biochemical Research

(E)-Guggulsterone is employed as a research tool in biochemistry to study various biological processes. Its use extends to understanding lipid metabolism and the mechanisms of cellular transport.

Cell Biology Studies

In cell biology, (E)-Guggulsterone serves as a probe for investigating cell signaling pathways and the regulation of gene expression. It is particularly relevant in studies concerning cholesterol metabolism and cellular responses.

Enzyme Inhibition Research

This compound is utilized to explore enzyme inhibition, with a focus on its potential modulatory effects on drug efflux pumps and multi-drug resistance mechanisms in cells.

02 /Properties

Molecular weight	312.45
Empirical formula	C21H28O2
Assay	≥95% (HPLC)
Form	powder
Colour	white to off-white
Solubility	DMSO: soluble5 mg/mL
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H335May cause respiratory irritation
H412Harmful to aquatic life with long-lasting effects

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P273Avoid release to the environment

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	37-52/53
Safety statements (S)	61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

39025-24-6

MDL number

MFCD01310758

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (E)-Guggulsterone used for?

(E)-Guggulsterone is used in biochemical research and cell biology studies, particularly for investigating cell signaling, cholesterol metabolism, and enzyme inhibition, including its role in multi-drug resistance.

What are the CAS number and molecular formula of (E)-Guggulsterone?

The CAS number for (E)-Guggulsterone is 39025-24-6, and its molecular formula is C21H28O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (E)-Guggulsterone with a purity of ≥95% by HPLC. This product is intended for research use and is not represented as USP, BP, or EP grade.

What are the safety and handling considerations for (E)-Guggulsterone?

As per GHS classification, (E)-Guggulsterone is a Warning substance. It may cause respiratory irritation (H335) and is harmful to aquatic life with long-lasting effects (H412). Handle with appropriate personal protective equipment in a well-ventilated area and avoid release into the environment.