(R)-(+)-SKF-38393 hydrochloride
(R)-(+)-SKF-38393 hydrochloride (CAS: 81702-42-3), with the formula C16H17NO2 · HCl and a molecular weight of 291.77 g/mol, is an off-white to light tan solid. This selective dopamine D1 receptor agonist is primarily used in neurological research for its ability to modulate dopaminergic pathways. It is supplied by Tech Serve Solutions with an assay of ≥98% (HPLC), suitable for various laboratory applications.
Neuroscience Research
(R)-(+)-SKF-38393 hydrochloride serves as a valuable tool in neuroscience for studying dopamine receptor function. Its selectivity for the D1 receptor allows researchers to investigate the roles of this specific receptor subtype in various physiological and pathological processes within the central nervous system.
Dopaminergic Pathway Studies
This compound is utilised to explore the complexities of the dopaminergic system, which is implicated in conditions such as Parkinson's disease and schizophrenia. By acting as a D1 receptor agonist, it helps researchers understand the impact of dopamine signalling on behaviour, cognition, and motor control.
Pharmacological Investigations
As a well-characterised pharmacological agent, (R)-(+)-SKF-38393 hydrochloride is used in in vitro and in vivo studies to assess drug efficacy and mechanisms of action related to dopamine neurotransmission. Its specific activity profile makes it a key reagent for validating new therapeutic targets.
| Molecular weight | 291.77 |
|---|---|
| Empirical formula | C16H17NO2 · HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | off-white to light tan |
| Solubility | 0.1 M HCl: soluble1.2 mg/mLethanol: soluble3.4 mg/mLH2O: soluble5 mg/mLaqueous base: unstable |
| Optical activity | [α]22/D +16.1°, c = 1.2 in methanol(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-SKF-38393 hydrochloride used for?
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(R)-(+)-SKF-38393 hydrochloride is primarily used in neuroscience research as a selective dopamine D1 receptor agonist to study dopaminergic pathways and their involvement in various neurological functions and disorders.
What are the CAS number and formula for (R)-(+)-SKF-38393 hydrochloride?
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The CAS number is 81702-42-3, and the formula is C16H17NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-SKF-38393 hydrochloride with an assay of ≥98% (HPLC). TSS does not represent this product as USP, EP, BP, or any other pharmacopoeia grade.
What are the main safety hazards associated with (R)-(+)-SKF-38393 hydrochloride?
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This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used when handling it.
How is (R)-(+)-SKF-38393 hydrochloride packaged, shipped, and exported?
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This chemical is supplied as an off-white to light tan solid. As a global supplier, Tech Serve Solutions has extensive experience in packaging, shipping, and exporting fine chemicals worldwide, adhering to all relevant regulations.
How can I request a sample or quote for (R)-(+)-SKF-38393 hydrochloride?
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Please contact our sales team or use the online enquiry form on the Tech Serve Solutions website to request a sample or obtain a quote for (R)-(+)-SKF-38393 hydrochloride.
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