2-Fluoro-5-methylpyridine
2-Fluoro-5-methylpyridine (CAS: 2369-19-9), with the molecular formula C6H6FN and a molecular weight of 111.12, is a fluorinated heterocyclic compound. It serves as a valuable building block in organic synthesis. This pyridine derivative is primarily utilised in the research and development of novel chemical entities, particularly within the pharmaceutical and agrochemical sectors, owing to the unique electronic properties imparted by the fluorine atom and the pyridine ring.

Organic Synthesis Intermediate
2-Fluoro-5-methylpyridine is a versatile intermediate used in the synthesis of more complex organic molecules. Its reactivity allows for various functional group transformations, making it a useful component in multi-step synthetic pathways.
Pharmaceutical Research
This compound is employed in medicinal chemistry research for the development of new drug candidates. The incorporation of a fluoropyridine moiety can influence pharmacokinetic properties such as metabolic stability and bioavailability.
Agrochemical Development
The molecule finds application in the discovery and synthesis of novel agrochemicals. Fluorinated heterocycles are often investigated for their potential as herbicides, insecticides, or fungicides.
Materials Science
2-Fluoro-5-methylpyridine may be used in the design and synthesis of specialised materials where its unique electronic and structural properties can be leveraged.
| Molecular weight | 111.12 |
|---|---|
| Empirical formula | C6H6FN |
| Assay | 97% |
| Boiling point | 158-159 °C(lit.) |
| Density | 1.072 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4730(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 48 °C / 118.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-5-methylpyridine used for?
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2-Fluoro-5-methylpyridine is primarily used as a building block in organic synthesis, particularly in the research and development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for 2-Fluoro-5-methylpyridine?
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The CAS number for 2-Fluoro-5-methylpyridine is 2369-19-9, and its molecular formula is C6H6FN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-5-methylpyridine with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Fluoro-5-methylpyridine be handled?
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2-Fluoro-5-methylpyridine is a flammable liquid and vapour (H226), and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and ensure adequate ventilation. Avoid heat, sparks, and open flames.
Is 2-Fluoro-5-methylpyridine a controlled substance?
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The provided data does not indicate that 2-Fluoro-5-methylpyridine is a controlled substance.
How is 2-Fluoro-5-methylpyridine shipped and exported?
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2-Fluoro-5-methylpyridine is classified under UN 1993 (Flammable liquid, n.o.s.) with hazard class 3 and packing group III. Tech Serve Solutions offers global export services for this chemical.
How can I request a quote or sample?
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Please contact Tech Serve Solutions directly through our website or sales department to request a quote or a sample of 2-Fluoro-5-methylpyridine.
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