Dimethyl chlorophosphate
Dimethyl chlorophosphate (CAS 813-77-4) is a reactive organophosphorus compound with the linear formula (CH3O)2P(O)Cl and a molecular weight of 144.49 g/mol. Supplied by TSS at 96% assay, this chemical is primarily used as a building block in organic synthesis. Its properties make it valuable in the preparation of various phosphorus-containing intermediates and fine chemicals, serving as a key reagent in complex chemical transformations. It is supplied for laboratory and industrial research applications.
- IUPAC
- Dimethyl phosphorochloridate
- Synonyms
- Dimethyl phosphorochloridatePhosphorochloridic acid, dimethyl esterDimethyl chlorophosphonate

Organic Synthesis Reagent
Dimethyl chlorophosphate is a versatile reagent used in organic synthesis. It serves as a key intermediate for introducing the dimethylphosphoryl group into various organic molecules, facilitating the construction of complex structures.
Phosphorylation Agent
This compound acts as a phosphorylating agent in the synthesis of organophosphate derivatives. These derivatives can find applications in diverse fields requiring specialized phosphorus-containing compounds.
Chemical Intermediate
As an organic building block, it is employed in the multi-step synthesis of fine chemicals and pharmaceutical intermediates. Its reactivity allows for targeted chemical modifications.
| Molecular weight | 144.49 |
|---|---|
| Linear formula | (CH3O)2P(O)Cl |
| Assay | 96% |
| Boiling point | 80 °C/25 mmHg(lit.) |
| Density | 1.34 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.413(lit.) |


Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P302IF ON SKIN
- P305IF IN EYES
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2927 8(6.1) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-34 |
| Safety statements (S) | 7/9-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dimethyl chlorophosphate used for?
+
Dimethyl chlorophosphate is primarily used as a building block and reagent in organic synthesis, particularly for phosphorylation reactions and the preparation of various phosphorus-containing intermediates and fine chemicals.
What is the CAS number and formula for Dimethyl chlorophosphate?
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The CAS number for Dimethyl chlorophosphate is 813-77-4, and its linear formula is (CH3O)2P(O)Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dimethyl chlorophosphate with an assay of 96%. This is a technical grade material suitable for research and synthesis and is not represented as USP, BP, or EP grade.
How should Dimethyl chlorophosphate be handled safely?
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Dimethyl chlorophosphate is a dangerous substance requiring extreme caution. It is corrosive and toxic, with severe hazards including fatal ingestion, skin contact, and inhalation (H300-H310-H314-H330). Always use appropriate personal protective equipment, including full-face respirators, chemical-resistant gloves, and eye protection, and handle only in a well-ventilated area or fume hood.
Is Dimethyl chlorophosphate a controlled substance?
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The provided data does not indicate that Dimethyl chlorophosphate is a controlled substance. However, users should always verify local regulations regarding its handling and use.
How is Dimethyl chlorophosphate packed, shipped, and exported?
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Dimethyl chlorophosphate is packed and shipped according to stringent international regulations for hazardous materials, ensuring safe transport. TSS is experienced in exporting such chemicals globally.
How can I request a quote or sample for Dimethyl chlorophosphate?
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To request a quote or sample of Dimethyl chlorophosphate, please contact our sales team via the website or direct inquiry, providing your details and requirements.
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