Dimethyl chlorothiophosphate
Dimethyl chlorothiophosphate (CAS: 2524-03-0) is an organophosphorus compound with the linear formula (CH3O)2P(S)Cl and a molecular weight of 160.56 g/mol. This colourless liquid functions as a crucial phosphorylating agent and an intermediate in organic synthesis. Its reactivity makes it valuable in the preparation of various phosphorus-containing compounds, often employed in research and industrial chemical synthesis.
- IUPAC
- Dimethyl phosphorochloridothionate
- Synonyms
- Dimethyl phosphorochloridothionate

Organic Synthesis Intermediate
Serves as a key building block in the synthesis of complex organic molecules. It is particularly useful for introducing thiophosphate groups into various chemical structures.
Phosphorylating Agent
Effectively used to transfer a thiophosphoryl group. This capability is vital in the development of novel organophosphorus compounds with diverse applications.
Research and Development
A valuable reagent for laboratory-scale synthesis and exploration of new chemical pathways. Its specific reactivity profile aids in the study of organophosphorus chemistry.
| Molecular weight | 160.56 |
|---|---|
| Linear formula | (CH3O)2P(S)Cl |
| Assay | 97% |
| Boiling point | 66-67 °C/16 mmHg(lit.) |
| Density | 1.322 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.482(lit.) |
| Vapour pressure | 0.67 psi (20 °C) |


Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 105 °C / 221 °F |
| Transport (UN / ADR) | UN 2267 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-34 |
| Safety statements (S) | 23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dimethyl chlorothiophosphate used for?
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Dimethyl chlorothiophosphate (CAS: 2524-03-0) is primarily used as an intermediate in organic synthesis and as a phosphorylating agent for introducing thiophosphate groups into molecules.
What is the CAS number and formula for Dimethyl chlorothiophosphate?
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The CAS number is 2524-03-0 and its linear formula is (CH3O)2P(S)Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dimethyl chlorothiophosphate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Dimethyl chlorothiophosphate be handled?
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Dimethyl chlorothiophosphate is a Danger hazard (H301-H311-H314-H331). Handle with extreme care, using appropriate personal protective equipment including a face shield, full-face respirator, gloves, and goggles. Refer to the safety data sheet for comprehensive handling instructions.
How is Dimethyl chlorothiophosphate packed, shipped, and exported?
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As a global supplier and exporter, Tech Serve Solutions adheres to all relevant regulations for the safe packing, shipping, and export of chemicals like Dimethyl chlorothiophosphate (UN 2267, 6.1/PG 2).
How can I request a quote or sample?
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To request a quote or sample of Dimethyl chlorothiophosphate, please use the contact form on our website or call our sales department directly.
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