Dimethyl bromomalonate
Dimethyl bromomalonate (CAS: 868-26-8) is a key organic building block with the molecular formula BrCH(COOCH3)2 and a molecular weight of 211.01 g/mol. This ester is characterised by its malonate structure substituted with a bromine atom, making it a versatile reagent in organic synthesis. It is primarily employed as an intermediate in the creation of more complex molecules, particularly in the pharmaceutical and fine chemical sectors.
Organic Synthesis Intermediate
Dimethyl bromomalonate serves as a valuable synthon in carbon-carbon bond formation reactions. Its electrophilic nature, due to the bromine atom and adjacent ester groups, allows for facile nucleophilic substitution.
Pharmaceutical Precursor
This compound is utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs). It enables the introduction of specific functional groups required for therapeutic efficacy.
Fine Chemical Manufacturing
It finds application in the production of speciality chemicals where precise molecular architecture is essential. Its reactivity profile makes it suitable for diverse chemical transformations.
| Molecular weight | 211.01 |
|---|---|
| Linear formula | BrCH(COOCH3)2 |
| Assay | 90% |
| Grade | technical grade |
| Boiling point | 105-108 °C/11 mmHg(lit.) |
| Density | 1.601 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.460(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dimethyl bromomalonate used for?
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Dimethyl bromomalonate is primarily used as an intermediate in organic synthesis, particularly for the preparation of pharmaceuticals and fine chemicals.
What is the CAS number and formula for Dimethyl bromomalonate?
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The CAS number for Dimethyl bromomalonate is 868-26-8, and its linear formula is BrCH(COOCH3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dimethyl bromomalonate in technical grade with an assay of 90%.
How should Dimethyl bromomalonate be handled safely?
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Dimethyl bromomalonate causes severe skin burns and eye damage. Handle with appropriate personal protective equipment, including chemical-resistant gloves, eye protection (goggles, face shield), and respiratory protection. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for full details.
Is Dimethyl bromomalonate a controlled substance?
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The provided data does not indicate that Dimethyl bromomalonate is a controlled substance.
How is Dimethyl bromomalonate packed, shipped, and exported?
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Dimethyl bromomalonate is packed and shipped according to international regulations for hazardous materials, designated as UN 3265, Class 8, Packing Group II. TSS exports this chemical globally.
How can I request a sample or quote for Dimethyl bromomalonate?
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To request a sample or quote for Dimethyl bromomalonate, please contact the TSS sales team through our website or by phone.
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