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2-Fluoro-5-nitroaniline

CAS 369-36-8FC6H3(NO2)NH2Chemical Synthesis

2-Fluoro-5-nitroaniline (CAS: 369-36-8), with the molecular formula FC6H3(NO2)NH2 and a molecular weight of 156.11 g/mol, is a fluorinated aromatic amine. This compound serves as a valuable building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its specific substitution pattern makes it a key intermediate for creating more complex molecules requiring both fluorine and nitro functionalities.

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2-Fluoro-5-nitroaniline (FC6H3(NO2)NH2) — chemical structure, CAS 369-36-8; Chemistry, fine chemical supplied by Tech Serve Solutions
AminesBuilding BlocksChemical SynthesisFluorinated Building BlocksNitrogen CompoundsOrganic Building Blocks
01 /Applications

Pharmaceutical Intermediate

2-Fluoro-5-nitroaniline is employed in the synthesis of active pharmaceutical ingredients (APIs). Its structure is incorporated into molecules designed for various therapeutic applications.

Agrochemical Synthesis

This compound is utilised as a precursor in the development of new agrochemicals, including herbicides and pesticides. The presence of fluorine can enhance the efficacy and metabolic stability of these agents.

Organic Synthesis Building Block

As a versatile fluorinated building block, it is used in complex organic synthesis pathways for research and development purposes. It allows for the introduction of specific fluoro-nitro-aniline moieties.

02 /Properties
Molecular weight156.11
Linear formulaFC6H3(NO2)NH2
Assay98%
Melting point97-100 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H228Flammable solid
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Flash point91 °C / 195.8 °F
Transport (UN / ADR)UN 1325 4.1 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xi
Risk statements (R)11-36/37/38
Safety statements (S)16-26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
369-36-8
MDL number
MFCD00007652
PubChem substance
24849574
Beilstein registry
2803491
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Fluoro-5-nitroaniline used for?

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2-Fluoro-5-nitroaniline is primarily used as a building block in organic synthesis, notably in the development of pharmaceuticals and agrochemicals. It acts as a key intermediate for introducing fluoro-nitro-aniline structures into more complex molecules.

What is the CAS number and formula for 2-Fluoro-5-nitroaniline?

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The CAS number for 2-Fluoro-5-nitroaniline is 369-36-8, and its molecular formula is FC6H3(NO2)NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Fluoro-5-nitroaniline with an assay of 98%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.

How should 2-Fluoro-5-nitroaniline be handled safely?

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2-Fluoro-5-nitroaniline is a flammable solid and can cause skin irritation, serious eye irritation, and respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., N100 or P3 filter cartridges), in a well-ventilated area, keeping it away from ignition sources.

How is 2-Fluoro-5-nitroaniline packed, shipped, and exported?

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2-Fluoro-5-nitroaniline is carefully packed according to international shipping regulations for hazardous materials. As a dangerous good (UN 1325, Class 4.1, PG II), it is expertly handled for global export by Tech Serve Solutions.

How can I request a quote or sample for 2-Fluoro-5-nitroaniline?

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To request a quote or a sample of 2-Fluoro-5-nitroaniline, please contact our sales department through the website or by phone. Our team will be pleased to assist you with your specific requirements.

Need 2-Fluoro-5-nitroaniline in a specific grade or volume?