2-Fluoro-5-nitrobenzotrifluoride
2-Fluoro-5-nitrobenzotrifluoride (CAS: 400-74-8), with the chemical formula FC<sub>6</sub>H<sub>3</sub>(NO<sub>2</sub>)CF<sub>3</sub> and a molecular weight of 209.10, is a key fluorinated organic intermediate. It is primarily utilised in chemical synthesis as a building block for more complex molecules. Its structure, featuring a trifluoromethyl group and a nitro group on a fluorinated benzene ring, makes it valuable in the development of pharmaceuticals and agrochemicals.
- IUPAC
- 5-Nitro-α,α,α,2-tetrafluorotoluene
Pharmaceutical Intermediate
This compound serves as a crucial building block in the synthesis of various active pharmaceutical ingredients (APIs). Its unique structural features, including the trifluoromethyl and nitro groups, allow for the introduction of specific functionalities into drug candidates.
Agrochemical Synthesis
2-Fluoro-5-nitrobenzotrifluoride is employed in the development of novel agrochemicals, such as herbicides and insecticides. The fluorine and trifluoromethyl moieties can enhance the efficacy and metabolic stability of these agricultural products.
Organic Synthesis Reagent
As a versatile fluorinated building block, it finds application in a broad range of organic synthesis research and development projects. It enables the creation of complex organic molecules with specific electronic and steric properties.
| Molecular weight | 209.10 |
|---|---|
| Linear formula | FC6H3(NO2)CF3 |
| Assay | 98% |
| Boiling point | 105-110 °C/25 mmHg(lit.) |
| Density | 1.522 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.465(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 92 °C / 197.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-5-nitrobenzotrifluoride used for?
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2-Fluoro-5-nitrobenzotrifluoride is used as a building block in chemical synthesis, particularly for pharmaceuticals and agrochemicals.
What are the CAS number and chemical formula for 2-Fluoro-5-nitrobenzotrifluoride?
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The CAS number is 400-74-8, and the chemical formula is FC<sub>6</sub>H<sub>3</sub>(NO<sub>2</sub>)CF<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-5-nitrobenzotrifluoride with a minimum assay of 98%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Fluoro-5-nitrobenzotrifluoride be handled safely?
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This compound is classified as an irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including safety glasses, gloves, and a suitable respirator. Ensure adequate ventilation and avoid breathing vapours.
How is 2-Fluoro-5-nitrobenzotrifluoride packed, shipped, and exported?
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2-Fluoro-5-nitrobenzotrifluoride is packaged according to international shipping regulations for chemical substances and is exported globally by Tech Serve Solutions.
How can I request a sample or a quote for 2-Fluoro-5-nitrobenzotrifluoride?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.
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