Aminopyrazine
Aminopyrazine (CAS: 5049-61-6), with the molecular formula C4H5N3 and a molecular weight of 95.10 g/mol, is a heterocyclic organic compound. It serves as a valuable building block in chemical synthesis, particularly in the creation of more complex heterocyclic structures. Its primary documented application is as a substrate in a four-component synthesis to form imidazolidines. Tech Serve Solutions supplies this reagent with an assay of ≥97.0% (NT) for research and development purposes.
- IUPAC
- Pyrazinamine

Substrate in Imidazolidine Synthesis
Aminopyrazine is employed as a key substrate in a specific four-component reaction sequence designed for the efficient synthesis of imidazolidine derivatives. This application highlights its utility in constructing complex nitrogen-containing heterocyclic frameworks.
Heterocyclic Building Block
As a pyrazine derivative, Aminopyrazine functions as a versatile building block for organic chemists. It can be incorporated into various synthetic pathways to introduce the pyrazine moiety into larger molecules, facilitating the development of novel chemical entities.
Chemical Synthesis Intermediate
This compound is utilised in diverse chemical synthesis processes, acting as an intermediate for the preparation of more complex organic molecules. Its reactive nature makes it suitable for further functionalisation and elaboration in multi-step syntheses.
| Molecular weight | 95.10 |
|---|---|
| Empirical formula | C4H5N3 |
| Assay | ≥97.0% (NT) |
| Application | Substrate in a four-component synthesis of imidazolidines.1 |
| Melting point | 118-120 °C(lit.)118-120 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Aminopyrazine used for?
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Aminopyrazine is primarily used as a substrate in the four-component synthesis of imidazolidines and as a versatile building block in chemical synthesis, particularly for heterocyclic compounds.
What are the CAS number and molecular formula for Aminopyrazine?
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The CAS number for Aminopyrazine is 5049-61-6, and its molecular formula is C4H5N3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Aminopyrazine with an assay of ≥97.0% (NT). This product is intended for laboratory and research use and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should Aminopyrazine be handled safely?
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Aminopyrazine may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
How is Aminopyrazine packed, shipped, and exported?
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Aminopyrazine is carefully packed to maintain its integrity during transit. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all relevant shipping and export regulations.
How can I request a sample or quote for Aminopyrazine?
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To request a sample or a quote for Aminopyrazine, please contact our sales team through the website or by phone. We are happy to assist with your specific chemical requirements.
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