(S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis[di(3,5-xylyl)phosphino]-3,3′-bipyridine
(S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis[di(3,5-xylyl)phosphino]-3,3′-bipyridine (CAS: 443347-10-2), a sophisticated chiral phosphine ligand, plays a crucial role in asymmetric synthesis. With a molecular weight of 756.85 g/mol and an empirical formula of C46H50N2O4P2, this compound is primarily utilised as a key component in catalytic processes requiring high enantioselectivity, particularly in hydrogenation reactions. Its unique structure enables precise control over stereochemical outcomes in complex organic transformations.
- IUPAC
- (S)-Xylyl-P-Phos
- Synonyms
- (S)-Xylyl-P-Phos6′-Tetramethoxy-4,4′-bis[di(3,5-xylyl)phosphino]-3,3′-bipyridine
![(S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis[di(3,5-xylyl)phosphino]-3,3′-bipyridine (C46H50N2O4P2) — chemical structure, CAS 443347-10-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F443347-10-2.png&w=3840&q=75)
Asymmetric Hydrogenation Ligand
This bipyridine derivative serves as an essential chiral ligand in asymmetric hydrogenation catalysis. It facilitates the enantioselective reduction of various substrates, leading to the formation of chiral products with high optical purity.
Catalysis in Organic Synthesis
The compound is integral to advanced organic synthesis, enabling stereocontrolled reactions. It is particularly valuable in the production of pharmaceutical intermediates and fine chemicals where specific enantiomers are required.
Development of Chiral Catalysts
As a privileged ligand, it is employed in the design and synthesis of novel chiral transition metal complexes. These complexes act as highly efficient catalysts for a range of asymmetric transformations beyond hydrogenation.
| Molecular weight | 756.85 |
|---|---|
| Empirical formula | C46H50N2O4P2 |
| Assay | 97% |
| Application | Ligand employed in the asymmetic hydrogenation of |
| Melting point | 158-162 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis[di(3,5-xylyl)phosphino]-3,3′-bipyridine used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis, particularly for enantioselective hydrogenation reactions.
What are the CAS number and molecular formula for this bipyridine derivative?
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The CAS number is 443347-10-2 and the molecular formula is C46H50N2O4P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with a minimum purity of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should this chemical be handled safely?
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Warning: This compound may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and we can arrange for the shipment and export of this compound according to international regulations.
How can I request a sample or quote?
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To request a sample or a quote for (S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis[di(3,5-xylyl)phosphino]-3,3′-bipyridine, please contact our sales department through the website or by phone.
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