(S)-(−)-2,2′-Bis(methoxymethoxy)-1,1′-binaphthalene
(S)-(−)-2,2′-Bis(methoxymethoxy)-1,1′-binaphthalene (CAS: 142128-92-5) is a chiral BINOL derivative with a molecular weight of 374.43. This compound serves as a valuable building block in asymmetric synthesis and chiral catalysis. Its unique structure allows for the facile preparation of substituted BINOL derivatives, making it a key reagent for researchers and chemists developing stereoselective synthetic routes.
- Synonyms
- 142128-92-5(CH3OCH2OC10H6)2
Asymmetric Synthesis
This BINOL derivative is employed in asymmetric synthesis to construct chiral molecules with high enantioselectivity. Its structural features facilitate the generation of 3- or 3,3′-di-substituted BINOL products through directed metallation and electrophilic quenching.
Chiral Catalysis and Ligand Development
It acts as a precursor or component in the development of chiral catalysts and ligands. These systems are crucial for catalysing a variety of stereoselective transformations in organic chemistry.
Synthesis of BINOL Derivatives
The compound enables straightforward access to a range of substituted BINOL derivatives. These derivatives can be further functionalised for specific applications in catalysis and materials science.
| Molecular weight | 374.43 |
|---|---|
| Linear formula | (CH3OCH2OC10H6)2 |
| Assay | 97% |
| Optical activity | [α]20/D -90°, c = 1% in chloroform |
| Application | 3- or 3,3′-di-substituted products can be obtained easily via ortho-metallation and subsequent treatment with an electrophile to give the corresponding BINOL derivatives.1 |
| Melting point | 100-104 °C(lit.) |
Hazard statements
- H318Causes serious eye damage
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P501Dispose of contents and container per local regulations
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi,N |
| Risk statements (R) | 41-50/53 |
| Safety statements (S) | 25-26-36/39-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2,2′-Bis(methoxymethoxy)-1,1′-binaphthalene used for?
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It is primarily used as a building block in asymmetric synthesis and for the development of chiral catalysts and ligands, facilitating the synthesis of substituted BINOL derivatives.
What is the CAS number and molecular formula for this compound?
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The CAS number is 142128-92-5. The linear formula is (CH₃OCH₂OC₁₀H₆)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.
How should (S)-(−)-2,2′-Bis(methoxymethoxy)-1,1′-binaphthalene be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. This compound can cause serious eye damage (H318) and is toxic to aquatic life with long-lasting effects (H410).
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, ensures appropriate packaging for safe transport and export of fine chemicals in compliance with international regulations, including UN 3077 for transport.
How can I request a sample or a quote for this chemical?
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To request a sample or a quote, please contact our sales department via the website or phone. Provide the product name and CAS number (142128-92-5) for prompt service.
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