3,5-Dimethoxyphenylmagnesium chloride
3,5-Dimethoxyphenylmagnesium chloride (CAS 89981-17-9), with a molecular weight of 196.91 g/mol, is a Grignard reagent vital in organic synthesis. This organometallic compound, typically supplied as a 1.0 M solution in THF, is instrumental in forming new carbon-carbon bonds. Its utility spans complex molecule construction, making it a key intermediate in the development of pharmaceuticals and fine chemicals.
- Synonyms
- C8H9ClMgO23,5-Dimethoxyphenylmagnesium chloride, 1.0 M in THF
Carbon-Carbon Bond Formation
As a Grignard reagent, 3,5-Dimethoxyphenylmagnesium chloride readily adds to electrophilic carbon centres such as aldehydes, ketones, esters, and epoxides. This reaction is fundamental for constructing more complex organic structures.
Pharmaceutical Intermediate Synthesis
This compound serves as a crucial building block in the synthesis pathways of various active pharmaceutical ingredients (APIs). Its specific structure allows for targeted functionalisation in drug discovery and development.
Fine Chemical Production
3,5-Dimethoxyphenylmagnesium chloride is employed in the manufacture of specialised fine chemicals. Its reactivity enables the introduction of the 3,5-dimethoxyphenyl moiety into diverse molecular scaffolds.
Organometallic Chemistry Research
It is used in academic and industrial research settings to explore novel synthetic methodologies and to create complex organic molecules with specific electronic or steric properties.
| Molecular weight | 196.91 |
|---|---|
| Empirical formula | C8H9ClMgO2 |
| Density | 1.022 g/mL at 25 °C |
| Concentration | 1.0 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -15 °C / 5 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Dimethoxyphenylmagnesium chloride used for?
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3,5-Dimethoxyphenylmagnesium chloride is primarily used in organic synthesis for carbon-carbon bond formation, acting as a key intermediate in the production of pharmaceuticals and fine chemicals.
What is the CAS number and molecular formula for 3,5-Dimethoxyphenylmagnesium chloride?
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The CAS number is 89981-17-9, and its empirical formula (Hill Notation) is C8H9ClMgO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,5-Dimethoxyphenylmagnesium chloride typically as a 1.0 M solution in THF. We do not represent this product as USP, BP, or EP grade; it is supplied for technical and research purposes.
How should 3,5-Dimethoxyphenylmagnesium chloride be handled safely?
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This compound is highly flammable and can form explosive peroxides. Handle with appropriate personal protective equipment (PPE) in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet (SDS) for detailed handling instructions.
Is 3,5-Dimethoxyphenylmagnesium chloride flammable?
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Yes, it is highly flammable with a flash point of -15 °C (5 °F). Store and handle away from heat, sparks, open flames, and hot surfaces.
How is 3,5-Dimethoxyphenylmagnesium chloride packed and shipped?
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As a specialist global supplier and exporter, Tech Serve Solutions ensures secure and compliant packing and shipping of 3,5-Dimethoxyphenylmagnesium chloride according to international regulations for hazardous materials.
How can I request a quote or sample of 3,5-Dimethoxyphenylmagnesium chloride?
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Please contact our sales team through the website or by phone to request a quotation or a sample. Our team will assist you with your inquiry.
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