Glu-Val-Asn-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyloctanoyl]-Ala-Glu-Phe
Glu-Val-Asn-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyloctanoyl]-Ala-Glu-Phe (CAS 314266-76-7) is a peptide with a molecular weight of 892.99 g/mol and empirical formula C41H64N8O14. This compound is recognised for its role as an inhibitor of β-Secretase (BACE1), an enzyme implicated in the pathogenesis of Alzheimer's disease. It serves as a valuable tool in biochemical research for studying enzymatic mechanisms and developing potential therapeutic strategies.
- IUPAC
- OM99-2
- Synonyms
- 7-dimethyloctanoyl]-Ala-Glu-PheC41H64N8O14OM99-2
![Glu-Val-Asn-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyloctanoyl]-Ala-Glu-Phe (C41H64N8O14) — chemical structure, CAS 314266-76-7; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F314266-76-7.png&w=3840&q=75)
Biochemical Research Reagent
This compound is utilized in biochemical assays and studies to investigate the activity and inhibition of β-Secretase (BACE1). Its specific structure makes it useful for understanding enzyme kinetics and substrate interactions in research settings.
Neuroscience Research
As a β-Secretase inhibitor, Glu-Val-Asn-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyloctanoyl]-Ala-Glu-Phe is employed in neuroscience research. It aids in exploring the molecular mechanisms underlying neurodegenerative diseases, particularly those associated with amyloid-beta production.
Enzyme Inhibition Studies
The compound serves as a specific inhibitor for enzymatic studies, allowing researchers to probe the function of β-Secretase within cellular pathways. This is crucial for drug discovery efforts targeting enzymes involved in disease.
| Molecular weight | 892.99 |
|---|---|
| Empirical formula | C41H64N8O14 |
| Assay | >93% (HPLC) |
| Form | solid |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Glu-Val-Asn-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyloctanoyl]-Ala-Glu-Phe used for?
+
This compound is primarily used as a β-Secretase (BACE1) inhibitor in biochemical and neuroscience research, particularly for studying neurodegenerative diseases like Alzheimer's.
What are the CAS number and formula for this compound?
+
The CAS number is 314266-76-7, and the empirical formula is C41H64N8O14.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with an assay of >93% (HPLC). TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the safety and handling recommendations?
+
For safe handling, use eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. This compound is classified with WGK Germany 3.
How is this product typically shipped and exported?
+
This product is typically shipped and exported as a solid and stored at -20°C to maintain its integrity.
How can I request a sample or quote?
+
To request a sample or a quote for Glu-Val-Asn-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyloctanoyl]-Ala-Glu-Phe, please contact our sales department through the website or by phone.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents
