Gliotoxin from Gliocladium fimbriatum

CAS 67-99-2C13H14N2O4S2Biochemicals & Reagents

Gliotoxin from Gliocladium fimbriatum (CAS: 67-99-2) is a chemical compound with the formula C13H14N2O4S2 and a molecular weight of 326.39 g/mol. This substance is recognised for its ability to act as a noncompetitive inhibitor of the chymotrypsin-like activity of the 20S proteasome in vitro. It is supplied by Tech Serve Solutions with an assay of ≥98.0% by TLC, suitable for research and laboratory applications.

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Gliotoxin from Gliocladium fimbriatum (C13H14N2O4S2) — chemical structure, CAS 67-99-2; Life Science, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Proteasome Inhibition

Gliotoxin serves as a noncompetitive inhibitor of the chymotrypsin-like activity of the 20S proteasome. This action is observed in vitro and is a key characteristic for its use in biochemical research.

Biochemical Research

As a well-defined bioactive molecule, gliotoxin is utilised in various biochemical studies. Its specific inhibitory properties make it a valuable tool for investigating proteasome function and related cellular processes.

Antibacterial Research

Although primarily known for proteasome inhibition, gliotoxin has historical associations with antibacterial properties, making it a compound of interest in the study of microbial interactions and potential therapeutic avenues.

02 /Properties

Molecular weight	326.39
Empirical formula	C13H14N2O4S2
Assay	≥98.0% (TLC)
Solubility	chloroform: soluble10 mg/mL, clear, colorless
Storage temperature	2-8°C
Application	Noncompetitive inhibitor of the chymotrypsin-like activity of the 20S proteasome in vitro.

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3462 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

67-99-2

MDL number

MFCD00058534

PubChem substance

24895384

Beilstein registry

50675

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Gliotoxin from Gliocladium fimbriatum used for?

Gliotoxin from Gliocladium fimbriatum is used as a noncompetitive inhibitor of the chymotrypsin-like activity of the 20S proteasome in vitro and for general biochemical research.

What is the CAS number and chemical formula for Gliotoxin?

The CAS number for Gliotoxin is 67-99-2, and its chemical formula is C13H14N2O4S2.

What grade and purity does Tech Serve Solutions supply for Gliotoxin?

Tech Serve Solutions supplies Gliotoxin with an assay of ≥98.0% by TLC. We do not represent this product as USP, BP, or EP grade.

How should Gliotoxin be handled and stored?

Gliotoxin is classified as Danger (GHS06) and is toxic if swallowed (H301). Handle with appropriate personal protective equipment including eyeshields, faceshields, gloves, and a P2 respirator. Store at 2-8°C.