(S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine
(S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine (CAS 362524-23-0) is a chiral phosphine ligand with the molecular formula C38H34N2O4P2 and a molecular weight of 644.64 g/mol. This P-Phos derivative is highly valued for its role as a privileged ligand in asymmetric synthesis, particularly in catalytic hydrogenation reactions, facilitating the stereoselective formation of chiral molecules.
- IUPAC
- (S)-P-Phos
- Synonyms
- (S)-P-Phos6′,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine
Asymmetric Hydrogenation
This compound serves as an effective chiral ligand in transition metal-catalyzed asymmetric hydrogenation. It enables the stereoselective reduction of various substrates, yielding enantiomerically enriched products crucial for pharmaceutical and fine chemical synthesis.
Chiral Catalyst Development
As a privileged ligand, (S)-(-)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine is instrumental in the development of novel chiral catalysts. Its well-defined stereochemistry allows for precise control over reaction pathways and product chirality.
Ligand for Organic Synthesis
It is employed as a key ligand in diverse organic transformations requiring high enantioselectivity. Its structural features contribute to efficient catalytic cycles and high turnover numbers in various metal-mediated reactions.
| Molecular weight | 644.64 |
|---|---|
| Empirical formula | C38H34N2O4P2 |
| Assay | 97% |
| Optical activity | [α]20/D -98°, c = 1 in chloroform |
| Application | Ligand employed in the asymmetic hydrogenation of |
| Melting point | 261-265 °C |
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine used for?
+
(S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine is primarily used as a chiral ligand in asymmetric synthesis, particularly for asymmetric hydrogenation reactions, and in the development of chiral catalysts.
What are the CAS number and molecular formula of this compound?
+
The CAS number is 362524-23-0, and the molecular formula is C38H34N2O4P2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound at a minimum assay of 97%. We do not represent it as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated otherwise in the product specifications.
How should (S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine be handled?
+
Handle this compound with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves, in a well-ventilated area. It is classified as an irritant (Xi, R37).
Is this chemical available for export?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine.
How can I request a sample or quote?
+
Please contact our sales team via the website or email to request a sample or a quotation for (S)-(−)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis