(S)-(−)-1-Z-2-Oxo-5-imidazolidinecarboxylic acid

CAS 59760-01-9C12H12N2O5Chemical Synthesis

(S)-(−)-1-Z-2-Oxo-5-imidazolidinecarboxylic acid (CAS 59760-01-9), with the molecular formula C12H12N2O5, is a Z-protected imidazolidinone. This chiral building block is specifically designed for sequential N-alkylation reactions in asymmetric synthesis. Its precise stereochemistry makes it valuable in complex chemical syntheses where chirality is crucial for product efficacy and function. Available from Tech Serve Solutions, it serves as a key intermediate in advanced organic chemistry research and development.

IUPAC: (S)-(−)-2-Oxo-1,5-imidazolidinedicarboxylic acid 1-benzyl ester

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(S)-(−)-1-Z-2-Oxo-5-imidazolidinecarboxylic acid (C12H12N2O5) — chemical structure, CAS 59760-01-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksImidazolines/Imidazolidines

01 /Applications

Asymmetric Synthesis

Utilised as a chiral building block in asymmetric synthesis to introduce specific stereochemistry into target molecules. Its protected imidazolidinone structure facilitates controlled synthetic pathways.

Heterocyclic Chemistry

Serves as a valuable intermediate in the synthesis of complex heterocyclic compounds. The imidazolidinone core is a common motif in many biologically active molecules.

Pharmaceutical Intermediates

Acts as a precursor in the development of pharmaceutical agents, where precise control over chiral centres is essential for drug activity and safety.

Sequential N-Alkylation

Specifically designed for sequential N-alkylation, allowing for controlled introduction of different substituents onto the nitrogen atoms of the imidazolidinone ring.

02 /Properties

Molecular weight	264.23
Empirical formula	C12H12N2O5
Assay	98%
Optical activity	[α]24/D −63.0°, c = 2.5 in methanol
Application	Z-protected imidazolidinone for sequential N-alkylation.1
Melting point	189 °C (dec.)(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

59760-01-9

MDL number

MFCD00192373

PubChem substance

24864442

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-(−)-1-Z-2-Oxo-5-imidazolidinecarboxylic acid used for?

(S)-(−)-1-Z-2-Oxo-5-imidazolidinecarboxylic acid is primarily used as a Z-protected imidazolidinone for sequential N-alkylation in asymmetric synthesis and as a chiral building block in chemical synthesis.

What is the CAS number and formula for this compound?

The CAS number is 59760-01-9 and the empirical formula (Hill notation) is C12H12N2O5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with an assay of 98%. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade; it is suitable for research and technical applications.

What are the safety and handling recommendations?

This compound is a Warning irritant (H315, H319, H335). Use with a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes and seek medical advice.