(S)-(−)-1-Phenylethanol
(S)-(−)-1-Phenylethanol (CAS: 1445-91-6, C8H10O) is a chiral alcohol with a molecular weight of 122.16 g/mol. This compound is primarily utilised in asymmetric synthesis and as a chiral resolving reagent. Its specific optical rotation, [α]22/D -44.0°, is critical for stereoselective reactions, making it a valuable intermediate in the synthesis of complex organic molecules and pharmaceuticals. Tech Serve Solutions supplies this reagent with an assay of 97%.
- IUPAC
- (−)-Methyl phenyl carbinol,(S)-(−)-α-Methylbenzyl alcohol,(S)-(−)-sec-Phenylethyl alcohol
- Synonyms
- (S)-(−)-α-Methylbenzyl alcohol(−)-1-Phenylethanol(S)-(−)-sec-Phenylethyl alcohol

Asymmetric Synthesis
Serves as a chiral auxiliary or building block in stereoselective reactions, enabling the synthesis of enantiomerically enriched compounds crucial for pharmaceutical development.
Chiral Resolution
Employed as a resolving agent to separate enantiomers of racemic mixtures, facilitating the isolation of desired stereoisomers.
Organic Synthesis Intermediate
Acts as a versatile intermediate in the preparation of more complex organic molecules, leveraging its chiral centre for targeted synthesis.
| Molecular weight | 122.16 |
|---|---|
| Empirical formula | C8H10O |
| Assay | 97% |
| Boiling point | 88-89 °C/10 mmHg(lit.) |
| Density | 1.012 g/mL at 20 °C(lit.) |
| Optical activity | [α]22/D -44.0°, neat |
| Melting point | 9-11 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | UN 2937 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(−)-1-Phenylethanol used for?
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This compound is primarily used in asymmetric synthesis and as a chiral resolving reagent for separating enantiomers.
What is the CAS number and formula for (S)-(−)-1-Phenylethanol?
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The CAS number is 1445-91-6 and the empirical formula is C8H10O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(−)-1-Phenylethanol with an assay of 97%. This is a research grade chemical and is not represented as USP, BP, or EP.
How should (S)-(−)-1-Phenylethanol be handled safely?
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Handle with care. It is harmful if swallowed (H302), causes skin irritation (H315), and causes serious eye damage (H318). Always wear appropriate personal protective equipment, including eyeshields, face shields, and gloves. Ensure adequate ventilation.
Is (S)-(−)-1-Phenylethanol a controlled substance?
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The provided safety data does not indicate that (S)-(−)-1-Phenylethanol is a controlled substance.
How is (S)-(−)-1-Phenylethanol packed, shipped, and exported?
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Chemicals are carefully packed according to international shipping regulations and exported globally by Tech Serve Solutions.
How can I request a sample or quote for (S)-(−)-1-Phenylethanol?
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Please contact our sales team via the website or email to request a sample or a detailed quotation.
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