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(R)-(+)-Propranolol hydrochloride

CAS 13071-11-9C10H7OCH2CH(OH)CH2NHCH(CH3)2·HClBiochemicals & Reagents

(R)-(+)-Propranolol hydrochloride (CAS 13071-11-9) is a chiral beta-adrenergic antagonist with the molecular formula C16H21NO2·HCl and a molecular weight of 295.80 g/mol. This white crystalline powder is primarily recognised for its role as a pharmaceutical intermediate and active pharmaceutical ingredient (API) precursor. It serves as a key component in the synthesis of various medicinal compounds.

IUPAC
(R)-1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride
Synonyms
(R)-1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride
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(R)-(+)-Propranolol hydrochloride (C10H7OCH2CH(OH)CH2NHCH(CH3)2·HCl) — chemical structure, CAS 13071-11-9; Life Science, fine chemical supplied by Tech Serve Solutions
AdrenergicsAdrenergics - AntagonistsAntagonistsAstraZenecaBioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and Antibodies
01 /Applications

Pharmaceutical Intermediate

Used in the synthesis of various pharmaceutical agents, particularly those targeting cardiovascular and neurological conditions. Its specific stereochemistry is crucial for its biological activity.

Research Chemical

Employed in biochemical and pharmacological research to study beta-adrenergic receptor mechanisms and their associated physiological effects. It serves as a reference standard in analytical procedures.

Drug Candidate Synthesis

A building block for developing novel drug candidates with beta-blocking properties. Researchers utilise its structure to explore new therapeutic avenues.

02 /Properties
Molecular weight295.80
Linear formulaC10H7OCH2CH(OH)CH2NHCH(CH3)2·HCl
Assay≥98% (TLC)
Solubilityethanol: soluble10 mg/mLDMSO: H2O: soluble50 mg/mL (With heat. Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.)45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble8.0 mg/mL
Storage temperature2-8°C
Melting point196-198 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22
Safety statements (S)22-24/25

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
13071-11-9
MDL number
MFCD00064546
PubChem substance
24898124
Beilstein registry
5780490
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

(R)-(+)-Propranolol hydrochloride is used for?

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Primarily as a pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients and for use in pharmacological research.

What is the CAS number and molecular formula for (R)-(+)-Propranolol hydrochloride?

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The CAS number is 13071-11-9 and the molecular formula is C16H21NO2·HCl.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (R)-(+)-Propranolol hydrochloride with an assay of ≥98% (TLC). This product is supplied for research and development purposes and TSS does not represent it as USP, BP, EP or other pharmacopoeia grades.

How should (R)-(+)-Propranolol hydrochloride be handled?

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(R)-(+)-Propranolol hydrochloride is harmful if swallowed and may cause eye irritation. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid dust formation and inhalation.

Is (R)-(+)-Propranolol hydrochloride a controlled substance?

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The provided data does not indicate that (R)-(+)-Propranolol hydrochloride is a controlled substance.

How is (R)-(+)-Propranolol hydrochloride packed and shipped?

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This compound is typically stored at 2-8°C. Specific packing and shipping details for export are available upon request and are handled according to international regulations for chemical substances.

How can I request a quote or sample?

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Please contact our sales team through the website to request a quote or a sample of (R)-(+)-Propranolol hydrochloride.

Need (R)-(+)-Propranolol hydrochloride in a specific grade or volume?