(6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride
(6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride (CAS 69056-38-8) is a biochemical reagent with the molecular formula C9H15N5O3 · 2HCl and a molecular weight of 314.17 g/mol. This compound serves as a crucial cofactor in various biological processes. It is primarily utilized in biochemical research, particularly in enzymatic assays and studies related to metabolic pathways. Its specific chiral form, (6R), is important for its biological activity.
- IUPAC
- (6R)-BH4
- Synonyms
- 8-Tetrahydrobiopterin dihydrochloride69056-38-8C9H15N5O3 · 2HCl
Enzyme Activity Assays
Used as a buffer component for assaying tyrosine hydroxylase enzyme activity in biological samples, such as mouse brain tissues. This application is vital for understanding neurotransmitter synthesis.
Biochemical Screening
Identified as an activator compound from library screens, for example, in fluorogenic α-glucosidase assays. This highlights its potential role in enzyme modulation studies.
Cofactor in Biological Research
Serves as an essential cofactor in various enzymatic reactions within biological systems. Research often focuses on its role in nitric oxide synthesis and phenylalanine metabolism.
| Molecular weight | 314.17 |
|---|---|
| Empirical formula | C9H15N5O3 · 2HCl |
| Solubility | water, oxygen free: soluble19.60 - 20.40 mg/mL, clear to slightly hazy, colorless to faintly yellow |
| Storage temperature | −20°C |
| Application | (6R)-BH4 has been used as a buffer component for assaying tyrosine hydroxylase enzyme activity in mouse brain tissues3. (6R)-BH4 has also been identified as an activator compound from a LOPAC library screen using a fluorogenic α-glucosidase assay4. |
Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride used for?
+
(6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride is used as a buffer component for assaying tyrosine hydroxylase enzyme activity and as an activator in biochemical screening, such as fluorogenic α-glucosidase assays. It also functions as a cofactor in biological research.
What are the CAS number and formula for (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride?
+
The CAS number is 69056-38-8 and the empirical formula is C9H15N5O3 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical for research and analytical purposes. The specific grade and purity available are detailed in the product specifications. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride be handled safely?
+
This compound is classified as harmful if swallowed (H302) and requires careful handling. Wear appropriate personal protective equipment, including gloves and eye protection, and avoid ingestion. Store at −20°C as indicated.
Is this chemical available for export?
+
Yes, Tech Serve Solutions specialises in global supply and export of fine chemicals, including (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride.
How can I request a quote or sample?
+
Please contact our sales team via the website or direct inquiry to receive a quote or request a sample of (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis