Nimesulide

CAS 51803-78-2C13H12N2O5SBiochemicals & Reagents

Nimesulide (CAS: 51803-78-2), with the molecular formula C13H12N2O5S and a molecular weight of 308.31 g/mol, is a fine chemical supplied by Tech Serve Solutions. It is recognized for its role as a selective cyclooxygenase-2 (COX-2) inhibitor. This compound is primarily utilised in scientific research and development settings, particularly within biochemical and cell biology studies focusing on inflammatory pathways and enzyme inhibition.

IUPAC: N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide

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Nimesulide (C13H12N2O5S) — chemical structure, CAS 51803-78-2; Life Science, fine chemical supplied by Tech Serve Solutions

A to CApplication IndexArachidonic Acid CascadeBioactive Small MoleculesBiochemicals and ReagentsCell BiologyCell Signaling EnzymesCyclooxygenaseCyclooxygenase (COX) EnzymesCyclooxygenase Inhibitors

01 /Applications

Research Chemical

Nimesulide serves as a valuable tool in biochemical research, enabling studies into the mechanisms of inflammation and pain. Its selective COX-2 inhibitory activity makes it useful for investigating the arachidonic acid cascade.

Enzyme Inhibition Studies

Utilised in vitro for the study of cyclooxygenase enzymes (COX-1 and COX-2), Nimesulide aids in understanding enzyme kinetics and the development of new therapeutic agents targeting these pathways.

Cell Biology Applications

As a bioactive small molecule, Nimesulide can be applied in cell culture experiments to investigate cellular responses to inflammatory stimuli and the effects of COX inhibition on cell signalling.

02 /Properties

Molecular weight	308.31
Empirical formula	C13H12N2O5S
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22
Safety statements (S)	36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

51803-78-2

MDL number

MFCD00079470

05 /Additional specifications

Gene Information	human ... ALB(213), PTGS1(5742), PTGS2(5743)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Nimesulide used for?

Nimesulide is primarily used as a research chemical in biochemical and cell biology studies, particularly for investigating the arachidonic acid cascade and cyclooxygenase (COX) enzyme inhibition.

What is the CAS number and formula for Nimesulide?

The CAS number for Nimesulide is 51803-78-2, and its molecular formula is C13H12N2O5S.

What grade and purity does Tech Serve Solutions supply for Nimesulide?

Tech Serve Solutions supplies Nimesulide as a research-grade chemical. The specific assay or purity is detailed in the product's specifications; we do not represent it as USP, BP, or EP grade.

How should Nimesulide be handled and stored?

Nimesulide is classified with 'Danger' signal word and is toxic if swallowed (H301). It requires protective measures including a dust mask type N95 (US), eyeshields, faceshields, and gloves. Store at 2-8°C.