Nisoxetine hydrochloride
Nisoxetine hydrochloride (CAS: 57754-86-6), with the empirical formula C17H21NO2 · HCl and a molecular weight of 307.82 g/mol, is a white to beige solid. It functions as a biogenic amine transport inhibitor, primarily utilised in neurochemical research. Its solubility in water and ethanol makes it a versatile reagent for in vitro studies concerning neurotransmission and cell signalling pathways, particularly within neuroscience and obesity research.
- IUPAC
- (±)-γ-(2-Methoxyphenoxy)-N-methyl-benzenepropanamine hydrochloride,LY-94,939

Neuroscience Research
Nisoxetine hydrochloride serves as a selective norepinephrine reuptake inhibitor, valuable for studying the role of noradrenergic pathways in various neurological functions and disorders.
Cellular Signaling Studies
This compound aids in investigating cell signalling mechanisms, particularly those involving neurotransmitter transporters and their impact on cellular responses.
Obesity Research
As a neurotransmission modulator, Nisoxetine hydrochloride can be employed in research aimed at understanding the neurobiological underpinnings of appetite regulation and obesity.
Biochemical Assays
Its defined purity makes it suitable for use in biochemical assays and as a reference standard in analytical chemistry concerning biogenic amine transport.
| Molecular weight | 307.82 |
|---|---|
| Empirical formula | C17H21NO2 · HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to beige |
| Solubility | H2O: soluble20 mg/mLethanol: soluble50 mg/mL |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nisoxetine hydrochloride used for?
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Nisoxetine hydrochloride is primarily used as a selective norepinephrine reuptemake inhibitor in neuroscience research, cellular signaling studies, and obesity research. It is also employed in biochemical assays.
What is the CAS number and chemical formula for Nisoxetine hydrochloride?
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The CAS number for Nisoxetine hydrochloride is 57754-86-6 and its empirical formula is C17H21NO2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nisoxetine hydrochloride with a purity of ≥98% (HPLC). This product is suitable for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Nisoxetine hydrochloride be handled safely?
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When handling Nisoxetine hydrochloride, it is essential to use personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK Germany rating of 3, indicating it is hazardous.
How is Nisoxetine hydrochloride packed and shipped?
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Nisoxetine hydrochloride is carefully packed in appropriate containers suitable for its form as a solid and shipped in compliance with international regulations for chemical export. Please contact us for specific shipping details to your region.
How can I request a sample or quote for Nisoxetine hydrochloride?
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To request a sample or a quotation for Nisoxetine hydrochloride, please contact our sales department via the website or by phone, providing your contact details and the quantity required.
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