Nitrofurantoin

CAS 67-20-9C8H6N4O5Biochemicals & Reagents

Nitrofurantoin (CAS 67-20-9) is a synthetic nitrofuran antibacterial agent with the molecular formula C8H6N4O5 and a molecular weight of 238.16 g/mol. It appears as a yellow crystalline solid. This compound serves as a substrate in biochemical research for studying bacterial enzymatic activity, particularly its nitrofuran reductase pathway. It is utilised to investigate nitrofurantoin-induced toxicity and the development of antibiotic resistance in microorganisms.

IUPAC: N-(5-Nitro-2-furfurylidene)-1-aminohydantoin,Furadoxyl,Nitrofurantoine

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Nitrofurantoin (C8H6N4O5) — chemical structure, CAS 67-20-9; Life Science, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Research Tool in Microbiology

Nitrofurantoin is employed as a substrate to study bacterial nitrofuran reductase activity. This allows researchers to investigate the mechanisms by which active metabolites interact with DNA, ribosomal proteins, and cellular pro-oxidant processes.

Investigation of Antibiotic Resistance

This compound is used in laboratory settings to study the development and mechanisms of antibiotic resistance. Research can explore how bacteria evolve to withstand the effects of nitrofuran-based agents like Nitrofurantoin.

Study of Drug-Induced Toxicity

Nitrofurantoin serves as a model compound for investigating drug-induced toxicity. Researchers can examine the cellular and molecular processes underlying the toxic effects of this antibiotic in biological systems.

02 /Properties

Molecular weight	238.16
Empirical formula	C8H6N4O5
Form	crystalline
Colour	yellow
Application	Nitrofurantoin is a nitrofuran antibiotic that is used as a substrate of bacterial nitrofuran reductase to study the interactions of active metabolites with DNA, ribosomal proteins and metabolic and pro-oxidant processes. It is used to study nitrofurantoin-induced toxicity 1 and antiobiotic resistance2.

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms if inhaled

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P280Wear protective gloves, clothing and eye/face protection
P342

Protective equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)	1
Hazard codes (EU)	Xn
Risk statements (R)	22-42/43
Safety statements (S)	22-36/37-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

67-20-9

MDL number

MFCD00003224

PubChem substance

24897842

Beilstein registry

893207

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Nitrofurantoin used for?

Nitrofurantoin is used in research to study bacterial nitrofuran reductase activity, nitrofurantoin-induced toxicity, and antibiotic resistance. It acts as a substrate in these investigations.

What are the CAS number and formula for Nitrofurantoin?

The CAS number for Nitrofurantoin is 67-20-9, and its empirical formula is C8H6N4O5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Nitrofurantoin as a yellow crystalline solid. The precise assay and purity are available on the Certificate of Analysis upon request. We do not represent this product as USP, BP, or EP grade.

How should Nitrofurantoin be handled safely?

Nitrofurantoin is classified as harmful if swallowed and may cause an allergic skin reaction and respiratory sensitisation. Handling requires a dust mask type N95 (US), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid breathing dust. Use P261, P280, and P342 + P311 precautionary statements.

How is Nitrofurantoin packed and exported?

Nitrofurantoin is carefully packed to maintain its integrity during transit and is available for global export by Tech Serve Solutions, a specialist supplier since 1998.