Nogalamycin
Nogalamycin (CAS 1404-15-5), a complex anthracycline antibiotic with the empirical formula C39H49NO16 and a molecular weight of 787.80, is isolated from Streptomyces nogalater. It functions by interfering with DNA synthesis and inhibiting key enzymes. Its primary application lies in its antineoplastic properties, making it a compound of interest for research in cancer therapeutics and related biological studies.
Antineoplastic Research
Nogalamycin is investigated for its potential as an antineoplastic agent due to its ability to interfere with DNA synthesis. It serves as a valuable tool in cancer research for understanding cellular mechanisms and exploring new therapeutic strategies.
Biochemical Research
As a complex natural product, Nogalamycin is utilised in biochemical studies to elucidate enzyme inhibition pathways and explore its interaction with nucleic acids. This aids in understanding fundamental biological processes.
Mechanism of Action Studies
The compound's known effects on DNA synthesis and enzyme inhibition make it suitable for detailed research into molecular mechanisms of antibiotic action. Such studies contribute to broader knowledge in microbiology and pharmacology.
| Molecular weight | 787.80 |
|---|---|
| Empirical formula | C39H49NO16 |
| Assay | ≥95% |
| Storage temperature | 2-8°C |
| Biological source | from Streptomyces nogalater |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
- H350May cause cancer
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P280Wear protective gloves, clothing and eye/face protection
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-46-61-20/21/22 |
| Safety statements (S) | 53-22-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nogalamycin primarily used for?
+
Nogalamycin is primarily used in antineoplastic and biochemical research due to its ability to inhibit enzymes and interfere with DNA synthesis.
What are the CAS number and formula for Nogalamycin?
+
The CAS number for Nogalamycin is 1404-15-5, and its empirical formula is C39H49NO16.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Nogalamycin with an assay of ≥95%. This product is supplied for research and laboratory purposes and is not represented as pharmacopoeia grade (e.g., USP, BP, EP).
How should Nogalamycin be handled and stored?
+
Nogalamycin is classified as Danger (GHS07, GHS08) with hazards including H302, H312, H332, H350, and H360. It requires careful handling with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. Store at 2-8°C.
How is Nogalamycin exported by TSS?
+
Tech Serve Solutions, as a global supplier and exporter, can ship Nogalamycin internationally, adhering to all necessary regulations for chemical export.
How can I request a quote or sample for Nogalamycin?
+
To request a quote or sample of Nogalamycin, please contact our sales department through the website or by phone, providing your required quantity and shipping details.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis