(R)-4-Fluoro-α-methylbenzyl alcohol
(R)-4-Fluoro-α-methylbenzyl alcohol (CAS: 101219-68-5) is a chiral fluorinated building block with the molecular formula FC6H4CH(CH3)OH and a molecular weight of 140.15. This optically active alcohol is valuable in asymmetric synthesis and as an intermediate in the preparation of more complex organic molecules. Its applications span chemical synthesis and research, particularly where specific stereochemistry and the presence of a fluorine atom are required for targeted molecular design.
- IUPAC
- (R)-1-(4′-Fluorophenyl)ethanol
- Synonyms
- (R)-1-(4′-Fluorophenyl)ethanol
Chiral Building Block in Organic Synthesis
(R)-4-Fluoro-α-methylbenzyl alcohol serves as a key chiral intermediate. Its defined stereochemistry is crucial for constructing enantiomerically pure target molecules in pharmaceutical and agrochemical research.
Intermediate for Fluorinated Compounds
The incorporation of fluorine can significantly alter the properties of organic molecules. This alcohol is used in the synthesis of advanced materials and biologically active compounds where fluorination is desired.
Research and Development
This compound is utilized in academic and industrial research laboratories for exploring new synthetic routes and developing novel chemical entities. Its structure offers versatility for further functionalization.
| Molecular weight | 140.15 |
|---|---|
| Linear formula | FC6H4CH(CH3)OH |
| Assay | 97% |
| Boiling point | 90-92 °C/7 mmHg |
| Density | 1.111 g/mL at 25 °C |
| Refractive index | n20/D 1.502 |
| Optical activity | [α]20/D +50°, c = 1 in chloroform |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-4-Fluoro-α-methylbenzyl alcohol used for?
+
(R)-4-Fluoro-α-methylbenzyl alcohol is primarily used as a chiral building block in organic synthesis, particularly in the development of fluorinated compounds for pharmaceutical and agrochemical research.
What is the CAS number and formula for (R)-4-Fluoro-α-methylbenzyl alcohol?
+
The CAS number is 101219-68-5, and the linear formula is FC6H4CH(CH3)OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-4-Fluoro-α-methylbenzyl alcohol with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
+
This compound is a Warning substance (GHS07) and is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (e.g., ABEK filters), should be used. Handle in a well-ventilated area.
How is (R)-4-Fluoro-α-methylbenzyl alcohol typically packed and shipped?
+
Tech Serve Solutions professionally packs and exports fine chemicals globally. Specific packaging details are available upon request, adhering to all relevant shipping regulations for NA 1993 / PGIII.
How can I request a quote or sample?
+
To request a quote or a sample of (R)-4-Fluoro-α-methylbenzyl alcohol, please contact our sales team through the website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis