(R)-4-Fluoromandelic acid
(R)-4-Fluoromandelic acid (CAS: 32222-45-0) is a chiral organic compound with the molecular formula C8H7FO3. Possessing a molecular weight of 170.14 g/mol, it serves as a valuable building block in organic synthesis. Its applications primarily lie in the pharmaceutical and fine chemical industries, where it is used as an intermediate for the synthesis of more complex chiral molecules and active pharmaceutical ingredients (APIs).
- IUPAC
- 4-Fluoro-D-mandelic acid

Chiral Synthesis Intermediate
Utilised as a key intermediate in asymmetric synthesis, enabling the construction of enantiomerically pure complex molecules for pharmaceutical research and development.
Pharmaceutical Building Block
Serves as a precursor in the synthesis of various active pharmaceutical ingredients (APIs), contributing to the development of novel therapeutics.
Research and Development
Employed in academic and industrial laboratories for exploring new synthetic routes and developing innovative chemical entities.
| Molecular weight | 592.42 |
|---|---|
| Empirical formula | 8H7FO3 |
| Assay | ≥97.5% (HPLC)98% |
| Grade | produced by BASF |
| Optical purity | enantiomeric excess: ≥98.5% |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-4-Fluoromandelic acid primarily used for?
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(R)-4-Fluoromandelic acid is primarily used as a chiral building block and intermediate in organic synthesis, particularly in the pharmaceutical industry for the development of active pharmaceutical ingredients.
What is the CAS number and molecular formula for (R)-4-Fluoromandelic acid?
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The CAS number is 32222-45-0 and the molecular formula is C8H7FO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-4-Fluoromandelic acid with an assay of ≥97.5% (HPLC) and an optical purity (enantiomeric excess) of ≥98.5%. The product is produced by BASF. It is not represented as USP, BP, or EP grade.
What are the safety and handling recommendations for (R)-4-Fluoromandelic acid?
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(R)-4-Fluoromandelic acid is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always handle with appropriate personal protective equipment, ensure good ventilation, and avoid breathing dust/fume/gas/mist/vapours/spray.
How is (R)-4-Fluoromandelic acid packed and shipped?
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(R)-4-Fluoromandelic acid is carefully packed to ensure product integrity during transit and is exported globally by Tech Serve Solutions in compliance with international shipping regulations.
How can I request a sample or quote for (R)-4-Fluoromandelic acid?
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To request a sample or a quote for (R)-4-Fluoromandelic acid, please contact our sales team through the website or by phone, providing your specific requirements.
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