(R)-4-Fluoro-α-methylbenzylamine
(R)-4-Fluoro-α-methylbenzylamine (CAS: 374898-01-8; Formula: C8H10FN; MW: 139.17) is a fluorinated chiral amine building block. Produced by BASF, it is primarily utilised in asymmetric synthesis and the preparation of complex organic molecules. Its enantiomeric purity and specific stereochemistry make it valuable for creating stereochemically defined compounds in research and development settings, particularly within the pharmaceutical and agrochemical industries.
- IUPAC
- (8R)-1-(4-Fluorophenyl)ethylamine
Asymmetric Synthesis
This enantiomerically pure amine serves as a crucial chiral building block in asymmetric synthesis, enabling the stereoselective construction of complex molecules.
Pharmaceutical Intermediates
Its fluorinated structure and chiral centre make it a valuable intermediate in the synthesis of pharmacologically active compounds, where precise stereochemistry is critical for efficacy.
Organic Building Block
As a versatile organic building block, (R)-4-Fluoro-α-methylbenzylamine can be incorporated into a wide range of target molecules for various chemical research applications.
Fluorinated Compound Synthesis
The presence of fluorine offers unique properties, making this amine useful for synthesising novel fluorinated organic compounds with potential applications in materials science and medicinal chemistry.
| Molecular weight | 139.17 |
|---|---|
| Empirical formula | C8H10FN |
| Assay | ≥98.5% (GC) |
| Grade | produced by BASF |
| Optical purity | enantiomeric excess: ≥98.5% |
Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 2735PSN1 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C,N |
| Risk statements (R) | 22-34-51/53 |
| Safety statements (S) | 26-36/37/39-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-4-Fluoro-α-methylbenzylamine used for?
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It is primarily used as a chiral building block in asymmetric synthesis for creating stereochemically defined compounds, particularly in the development of pharmaceutical and agrochemical intermediates.
What is the CAS number and formula for (R)-4-Fluoro-α-methylbenzylamine?
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The CAS number is 374898-01-8, and the empirical formula is C8H10FN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical produced by BASF with an assay of ≥98.5% (GC) and an optical purity (enantiomeric excess) of ≥98.5%. It is not represented as USP, BP, or EP grade.
What are the safety and handling considerations for this chemical?
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This chemical is classified as Danger. It is harmful if swallowed (H302), causes severe skin burns and eye damage (H314), and is toxic to aquatic life with long-lasting effects (H411). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding release to the environment. Follow P273, P280, P305 + P351 + P338, and P310 precautionary statements.
Is (R)-4-Fluoro-α-methylbenzylamine a controlled substance?
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Based on the provided data, there is no indication that (R)-4-Fluoro-α-methylbenzylamine is a controlled substance. However, users should always verify current local regulations.
How can I request a sample or quote for (R)-4-Fluoro-α-methylbenzylamine?
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To request a sample or quote, please contact our sales team through the website or by calling us directly. Please specify the quantity required.
How is this chemical packed, shipped, and exported?
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This chemical is packed and shipped according to international dangerous goods regulations (UN 2735, PSN1 8 / PGII). Tech Serve Solutions is experienced in global export and can provide necessary documentation.
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