3-Fluoro-4-isopropoxyphenylboronic acid

CAS 480438-54-8C9H12BFO3Chemical Synthesis

3-Fluoro-4-isopropoxyphenylboronic acid (CAS: 480438-54-8, C9H12BFO3) is a valuable organic compound with a molecular weight of 198.00. As a substituted aryl boronic acid, it serves as a key building block in organic synthesis. Its applications are primarily focused on the preparation of complex molecules, including pharmaceutical intermediates via reactions like Suzuki and Stille couplings, and the synthesis of novel therapeutic agents.

IUPAC: 3-Fluoro-4-isopropoxybenzeneboronic acid,[3-Fluoro-4-(1-methylethoxy)phenyl]boronic acid
Synonyms: 3-Fluoro-4-isopropoxybenzeneboronic acid[3-Fluoro-4-(1-methylethoxy)phenyl]boronic acid

Email us

3-Fluoro-4-isopropoxyphenylboronic acid (C9H12BFO3) — chemical structure, CAS 480438-54-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Aryl Boronic AcidsBoronic AcidsChemical Synthesis

01 /Applications

Synthesis of Glucocorticoid Receptor Modulators

3-Fluoro-4-isopropoxyphenylboronic acid is utilised as a reactant in the synthesis of azaxanthene-based selective glucocorticoid receptor modulators, contributing to the development of new therapeutic compounds.

Cross-Coupling Reactions for Drug Discovery

This boronic acid is employed in Suzuki and Stille coupling reactions for the synthesis of various complex organic molecules, including those with potential as oral venous antithrombotic drugs.

Building Block in Pharmaceutical Synthesis

As a versatile aryl boronic acid derivative, it functions as a crucial intermediate in the multi-step synthesis pathways for developing new pharmaceutical agents and fine chemicals.

02 /Properties

Molecular weight	198.00
Empirical formula	C9H12BFO3
Application	Reactant involved in:• Synthesis of azaxanthene based selective glucocorticoid receptor modulators1• Suzuki and Stille coupling for synthesis of oral venous antithrombotic drugs2
Melting point	112-117 °C(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

480438-54-8

MDL number

MFCD05865163

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Fluoro-4-isopropoxyphenylboronic acid used for?

It is used as a reactant in organic synthesis, notably in the preparation of azaxanthene-based selective glucocorticoid receptor modulators and in Suzuki and Stille coupling reactions for the synthesis of oral venous antithrombotic drugs.

What are the CAS number and formula for this compound?

The CAS number is 480438-54-8 and the empirical formula (Hill notation) is C9H12BFO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound as a research or technical grade chemical. We do not represent it as USP, BP, EP, or for use in nutraceutical or food applications. Purity information is available upon request.

What are the safety and handling recommendations?

Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified with WGK 2 in Germany, indicating it is hazardous to water.

How is this chemical packed, shipped, and exported?

Tech Serve Solutions expertly packs and exports fine chemicals globally, adhering to all relevant shipping regulations. Specific packaging details are available upon request.

How can I request a sample or quote for 3-Fluoro-4-isopropoxyphenylboronic acid?

To request a sample or a quotation, please contact our sales team via the website or directly by phone. We are pleased to assist with your research and synthesis needs.