3-Fluoro-4-iodopyridine
3-Fluoro-4-iodopyridine (CAS: 22282-75-3) is a fluorinated heterocyclic building block with the molecular formula C5H3FIN and a molecular weight of 222.99 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its unique combination of fluorine and iodine substituents on the pyridine ring allows for diverse chemical transformations, making it a key component in constructing complex molecular architectures for research and development purposes.
- IUPAC
- 4-Iodo-3-fluoropyridine
- Synonyms
- 4-Iodo-3-fluoropyridine

Pharmaceutical Intermediates
3-Fluoro-4-iodopyridine is utilised in the synthesis of novel pharmaceutical compounds. Its structure facilitates regioselective functionalisation, enabling the creation of diverse drug candidates with potential therapeutic applications.
Agrochemical Development
This fluorinated pyridine derivative is employed in the research and development of new agrochemicals. The incorporation of fluorine can enhance the efficacy and metabolic stability of pesticides and herbicides.
Organic Synthesis Reagent
As a versatile building block, 3-Fluoro-4-iodopyridine is used in various organic transformations. The iodine atom can participate in cross-coupling reactions, while the fluorine atom influences the electronic properties of the pyridine ring.
Materials Science Research
The compound's unique electronic and structural properties make it of interest for developing novel materials. It can be incorporated into polymers or organic electronic components.
| Molecular weight | 222.99 |
|---|---|
| Empirical formula | C5H3FIN |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 85-89 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-4-iodopyridine used for?
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3-Fluoro-4-iodopyridine is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials. Its structure allows for versatile chemical transformations.
What is the CAS number and formula for 3-Fluoro-4-iodopyridine?
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The CAS number for 3-Fluoro-4-iodopyridine is 22282-75-3, and its empirical formula is C5H3FIN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-4-iodopyridine with a minimum assay of 97%. This product is typically intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should 3-Fluoro-4-iodopyridine be handled and stored?
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3-Fluoro-4-iodopyridine is classified as Danger, H314 (Causes severe skin burns and eye damage). It requires careful handling with appropriate personal protective equipment, including eyeshields, faceshields, chemical-resistant gloves, and respiratory protection. Store refrigerated at 2-8°C.
Is 3-Fluoro-4-iodopyridine a controlled substance?
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Based on the provided data, there is no indication that 3-Fluoro-4-iodopyridine is a controlled substance. However, users should always verify local regulations.
How is this chemical packed and exported?
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This chemical is packed and exported according to international transport regulations, classified as UN 3261, Class 8, Packing Group III. Specific packaging details can be provided upon request.
How can I request a sample or quote for 3-Fluoro-4-iodopyridine?
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To request a sample or a quote for 3-Fluoro-4-iodopyridine, please contact the Tech Serve Solutions sales department through our website or by phone, referencing the product name and CAS number.
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