3-Fluoro-4-hydroxyphenylacetic acid
3-Fluoro-4-hydroxyphenylacetic acid (CAS 458-09-3), with the molecular formula FC6H3(OH)CH2CO2H and a molecular weight of 170.14 g/mol, is a fluorinated organic building block. This compound serves as a versatile intermediate in organic synthesis, particularly in the development of novel pharmaceutical compounds and advanced materials. Its structure, featuring both a hydroxyl and a carboxylic acid group alongside a fluorine atom on the phenyl ring, allows for diverse chemical modifications and applications.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the fluoro-phenyl moiety is a key structural feature. It can be incorporated into drug candidates targeting various therapeutic areas.
Agrochemical Synthesis
Acts as a building block for creating new agrochemical agents, contributing to the development of pesticides, herbicides, and fungicides with enhanced efficacy or novel modes of action.
Material Science
Incorporated into the design and synthesis of functional materials and polymers, leveraging the unique electronic and physical properties imparted by the fluorine atom and phenolic hydroxyl group.
Research and Development
A valuable reagent for academic and industrial research laboratories exploring new synthetic routes and developing novel chemical entities for diverse scientific applications.
| Molecular weight | 170.14 |
|---|---|
| Linear formula | FC6H3(OH)CH2CO2H |
| Assay | 98% |
| Melting point | 132-134 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-4-hydroxyphenylacetic acid used for?
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3-Fluoro-4-hydroxyphenylacetic acid is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials.
What are the CAS number and chemical formula for 3-Fluoro-4-hydroxyphenylacetic acid?
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The CAS number is 458-09-3 and the chemical formula is FC6H3(OH)CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-4-hydroxyphenylacetic acid with an assay of 98%. This product is not represented as USP, BP, or EP grade.
How should 3-Fluoro-4-hydroxyphenylacetic acid be handled?
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Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation. Avoid breathing dust. This compound is classified as an irritant to the skin, eyes, and respiratory system.
Is 3-Fluoro-4-hydroxyphenylacetic acid exported by TSS?
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Yes, Tech Serve Solutions specialises in the global supply and export of fine chemicals, including 3-Fluoro-4-hydroxyphenylacetic acid.
How can I request a sample or quote for 3-Fluoro-4-hydroxyphenylacetic acid?
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Please contact our sales team through the website or by phone to request a sample or a quotation for 3-Fluoro-4-hydroxyphenylacetic acid.
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