3-Fluoro-4-(trifluoromethyl)pyridine
3-Fluoro-4-(trifluoromethyl)pyridine (CAS: 113770-87-9, C6H3F4N) is a fluorinated heterocyclic compound with a molecular weight of 165.09 g/mol. This pyridine derivative serves as a valuable building block in organic synthesis, particularly for introducing fluorinated motifs into more complex molecules. Its unique structural features make it useful in the development of novel compounds for research and chemical manufacturing.

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. Its trifluoromethyl and fluoro substituents offer specific reactivity for targeted chemical transformations.
Pharmaceutical Research
Serves as a building block in the discovery and development of new pharmaceutical agents. The incorporation of fluorine can significantly alter the pharmacokinetic properties of drug candidates.
Agrochemical Development
A valuable precursor in the creation of novel agrochemicals. Fluorinated heterocycles are often employed to enhance the efficacy and stability of pesticides and herbicides.
Material Science
Can be incorporated into the synthesis of advanced materials where specific electronic or physical properties are desired, owing to the presence of fluorine.
| Molecular weight | 165.09 |
|---|---|
| Empirical formula | C6H3F4N |
| Assay | 97% |
| Boiling point | 37 °C/10 mmHg |
| Density | 1.391 g/mL at 25 °C |
| Refractive index | n20/D 1.406 |


Hazard statements
- H225Highly flammable liquid and vapour
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 20 °C / 68 °F |
| Transport (UN / ADR) | UN 1992 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,T |
| Risk statements (R) | 11-25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-4-(trifluoromethyl)pyridine used for?
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3-Fluoro-4-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials.
What are the CAS number and formula for 3-Fluoro-4-(trifluoromethyl)pyridine?
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The CAS number is 113770-87-9 and the molecular formula is C6H3F4N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-4-(trifluoromethyl)pyridine with an assay of 97%. This product is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 3-Fluoro-4-(trifluoromethyl)pyridine be handled safely?
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This compound is highly flammable (Flash point 20 °C) and toxic if swallowed (Danger, H225-H300). Handling requires stringent safety measures, including appropriate personal protective equipment such as eyeshields, gloves, and respiratory protection. Work in a well-ventilated area.
Is 3-Fluoro-4-(trifluoromethyl)pyridine exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Fluoro-4-(trifluoromethyl)pyridine.
How can I request a sample or quote for 3-Fluoro-4-(trifluoromethyl)pyridine?
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To request a sample or a quotation, please contact our sales team directly through the TSS website or by phone.
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