3-Fluoro-4-(trifluoromethyl)benzoyl chloride
3-Fluoro-4-(trifluoromethyl)benzoyl chloride (CAS: 216144-68-2) is a fluorinated organic compound with the linear formula FC<sub>6</sub>H<sub>3</sub>(CF<sub>3</sub>)COCl and a molecular weight of 226.56 g/mol. As an acid halide and reactive carbonyl compound, it serves as a key intermediate and building block in organic synthesis, particularly for introducing fluorinated aromatic moieties into larger molecules. Its utility spans diverse chemical research and development sectors.
Organic Synthesis Intermediate
This compound functions as a versatile building block for synthesising complex organic molecules. It is particularly useful in introducing the 3-fluoro-4-(trifluoromethyl)phenyl group into target structures through acylation reactions.
Fluorinated Compound Development
Its fluorinated nature makes it valuable in the development of novel fluorinated compounds, which often exhibit unique properties beneficial in pharmaceuticals, agrochemicals, and materials science.
Research and Development
Widely employed in R&D laboratories, this reagent supports the exploration of new chemical pathways and the creation of novel chemical entities.
| Molecular weight | 226.56 |
|---|---|
| Linear formula | FC6H3(CF3)COCl |
| Assay | 95% |
| Boiling point | 152 °C(lit.) |
| Density | 1.486 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.465(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 87 °C / 188.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-4-(trifluoromethyl)benzoyl chloride primarily used for?
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3-Fluoro-4-(trifluoromethyl)benzoyl chloride is primarily used as an intermediate and building block in organic synthesis, particularly for introducing fluorinated aromatic groups into target molecules.
What are the CAS number and formula for this compound?
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The CAS number is 216144-68-2, and its linear formula is FC6H3(CF3)COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-4-(trifluoromethyl)benzoyl chloride with a minimum assay of 95%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 3-Fluoro-4-(trifluoromethyl)benzoyl chloride be handled safely?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). It requires appropriate personal protective equipment, including faceshields, goggles, gloves, and suitable respiratory protection. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
How is 3-Fluoro-4-(trifluoromethyl)benzoyl chloride packed, shipped, and exported?
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This chemical is packed in compliance with UN 3265, Class 8, Packing Group II regulations. Tech Serve Solutions is experienced in exporting chemicals globally.
How can I request a sample or quote for this chemical?
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To request a sample or a quote, please contact our sales team through the website or by phone. Specify the product name and CAS number for prompt service.
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