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2-Bromo-4′-chloroacetophenone

CAS 536-38-9ClC6H4COCH2BrChemical Synthesis

2-Bromo-4′-chloroacetophenone (CAS: 536-38-9) is a valuable organic compound with the molecular formula ClC₆H₄COCH₂Br and a molecular weight of 233.49 g/mol. It serves as a key building block in organic synthesis, particularly in the preparation of various chemical intermediates. This ketone derivative is recognised for its utility in creating more complex molecular structures for research and development purposes.

IUPAC
ω-Bromo-4-chloroacetophenone,4-Chlorophenacyl bromide
Synonyms
4-Chlorophenacyl bromideω-Bromo-4-chloroacetophenone
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2-Bromo-4′-chloroacetophenone (ClC6H4COCH2Br) — chemical structure, CAS 536-38-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC7 to C8Carbonyl CompoundsChemical SynthesisKetones
01 /Applications

Organic Synthesis Intermediate

2-Bromo-4′-chloroacetophenone is widely employed as an intermediate in the synthesis of complex organic molecules. Its reactive bromo-ketone functionality allows for versatile chemical transformations.

Research and Development

This compound is a useful reagent for academic and industrial research laboratories exploring new synthetic pathways and novel chemical entities. It enables the construction of diverse molecular scaffolds.

Pharmaceutical Precursor

It can act as a precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) and other biologically relevant compounds. Its structure lends itself to derivatisation for drug discovery efforts.

02 /Properties
Molecular weight233.49
Linear formulaClC6H4COCH2Br
Assay98%
Melting point93-96 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)UN 3261 8 / PGII
Water hazard class (WGK, DE)2
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
536-38-9
MDL number
MFCD00000625
PubChem substance
24846535
Beilstein registry
607603
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Bromo-4′-chloroacetophenone used for?

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2-Bromo-4′-chloroacetophenone is primarily used as a building block and intermediate in organic synthesis, research and development, and as a potential precursor in the pharmaceutical industry.

What are the CAS number and chemical formula?

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The CAS number is 536-38-9, and the linear formula is ClC₆H₄COCH₂Br.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Bromo-4′-chloroacetophenone with an assay of 98%. This product is suitable for research and technical applications. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.

How should 2-Bromo-4′-chloroacetophenone be handled safely?

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2-Bromo-4′-chloroacetophenone is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (type N100 or P3 filter), must be used. Handle only in a well-ventilated area.

How is this chemical packed and shipped?

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Tech Serve Solutions carefully packs and exports chemicals according to international shipping regulations. For 2-Bromo-4′-chloroacetophenone, it is shipped under UN 3261, 8, PGII.

How can I request a quote or sample?

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To request a quote or a sample of 2-Bromo-4′-chloroacetophenone, please contact our sales department through the website or by phone, providing your specific requirements.

Need 2-Bromo-4′-chloroacetophenone in a specific grade or volume?