2-Bromo-4′-methoxyacetophenone
2-Bromo-4′-methoxyacetophenone (CAS: 2632-13-5) is a chemical compound with the molecular formula CH₃OC₆H₄COCH₂Br and a molecular weight of 229.07 g/mol. This methoxyacetophenone derivative serves as a valuable building block and intermediate in organic synthesis, particularly within the fields of chemical synthesis and cell biology. It is recognised for its utility in creating complex molecular structures, including photocleavable polymers.
- IUPAC
- ω-Bromo-4-methoxyacetophenone,4-Methoxyphenacyl bromide
- Synonyms
- 4-Methoxyphenacyl bromideω-Bromo-4-methoxyacetophenone

Synthesis of Photolabile Polymers
2-Bromo-4′-methoxyacetophenone has been employed in the synthesis of light-responsive diblock copolymers. These materials incorporate para-methoxyphenacyl photocleavable side groups, enabling controlled degradation or modification upon exposure to specific light wavelengths.
Organic Synthesis Intermediate
As a functionalised ketone, this compound is a useful intermediate in multi-step organic synthesis pathways. Its bromo and methoxyacetophenone functionalities allow for diverse chemical transformations and the construction of more complex molecular architectures.
Research and Development
This chemical is utilised in research laboratories for exploring novel synthetic routes and developing new bioactive molecules. Its structure makes it a versatile starting material for various chemical investigations.
| Molecular weight | 229.07 |
|---|---|
| Linear formula | CH3OC6H4COCH2Br |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | 2-Bromo-4′-methoxyacetophenone has been used in the synthesis of light-responsive diblock copolymers containing para-methoxyphenacyl photocleavable side groups1. |
| Melting point | 69-71 °C(lit.) |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PTPN6(5777) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-4′-methoxyacetophenone used for?
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2-Bromo-4′-methoxyacetophenone is used as a building block in organic synthesis, particularly for creating light-responsive polymers and as an intermediate in chemical research and development.
What is the CAS number and chemical formula for 2-Bromo-4′-methoxyacetophenone?
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The CAS number is 2632-13-5 and the linear chemical formula is CH₃OC₆H₄COCH₂Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-4′-methoxyacetophenone with an assay of 97%. This product is supplied for research and technical purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
How should 2-Bromo-4′-methoxyacetophenone be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, as it is corrosive and may cause respiratory irritation. Store at 2-8°C.
Is 2-Bromo-4′-methoxyacetophenone subject to special shipping regulations?
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Yes, this compound is shipped as UN 3261, Class 8, Packing Group II, indicating it is a corrosive solid, acidic, organic, n.o.s. (2-Bromo-4′-methoxyacetophenone).
How can I request a quote or sample for 2-Bromo-4′-methoxyacetophenone?
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To request a quote or sample, please contact our sales team through the TSS website or by phone, providing the product name and CAS number (2632-13-5).
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