2-Bromo-4′-fluoroacetophenone
2-Bromo-4′-fluoroacetophenone (CAS 403-29-2) is a fluorinated organic building block with the linear formula FC <sub>6</sub> H <sub>4</sub> COCH <sub>2</sub> Br and a molecular weight of 217.04 g/mol. This compound serves as a valuable intermediate in chemical synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. Its reactivity makes it a key component for introducing fluorinated acetophenone moieties into larger molecular structures, facilitating research in medicinal chemistry and materials science.
- IUPAC
- ω-Bromo-4-fluoroacetophenone,4-Fluorophenacyl bromide
- Synonyms
- 4-Fluorophenacyl bromideω-Bromo-4-fluoroacetophenone

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its structure allows for further functionalisation in the development of complex therapeutic agents.
Agrochemical Development
Serves as a building block for novel pesticides, herbicides, and fungicides. The incorporation of fluorine can enhance the biological activity and stability of agrochemical compounds.
Organic Synthesis Reagent
A versatile reagent for introducing the 4-fluorophenacyl group into various organic molecules. Employed in academic and industrial research laboratories for custom synthesis projects.
Material Science
Investigated for its potential in the development of new materials with specific electronic or optical properties, owing to its fluorinated aromatic structure.
| Molecular weight | 217.04 |
|---|---|
| Linear formula | FC6H4COCH2Br |
| Assay | 97% |
| Boiling point | 150 °C/12 mmHg(lit.) |
| Melting point | 47-49 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... PTPN6(5777) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-4′-fluoroacetophenone used for?
+
2-Bromo-4′-fluoroacetophenone (CAS 403-29-2) is primarily used as an intermediate in organic synthesis, particularly for developing pharmaceuticals, agrochemicals, and materials science applications.
What is the CAS number and formula for 2-Bromo-4′-fluoroacetophenone?
+
The CAS number is 403-29-2 and the linear formula is FC <sub>6</sub> H <sub>4</sub> COCH <sub>2</sub> Br.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-Bromo-4′-fluoroacetophenone with an assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Bromo-4′-fluoroacetophenone be handled?
+
2-Bromo-4′-fluoroacetophenone is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment including eyeshields, face shields, chemical-resistant gloves, and respiratory protection (e.g., N100 respirator) must be used. Handle only in a well-ventilated area.
How is 2-Bromo-4′-fluoroacetophenone packed, shipped, and exported?
+
This compound is packed according to stringent international safety standards for hazardous materials, including UN 3261 classification. We are experienced exporters and can provide necessary documentation for global shipment.
How can I request a sample or quote for 2-Bromo-4′-fluoroacetophenone?
+
Please contact our sales team directly via email or phone to request a sample or a quotation. Provide your specific requirements and shipping details for prompt processing.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis