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2-Bromo-4′-fluoroacetophenone

CAS 403-29-2FC6H4COCH2BrChemical Synthesis

2-Bromo-4′-fluoroacetophenone (CAS 403-29-2) is a fluorinated organic building block with the linear formula FC <sub>6</sub> H <sub>4</sub> COCH <sub>2</sub> Br and a molecular weight of 217.04 g/mol. This compound serves as a valuable intermediate in chemical synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. Its reactivity makes it a key component for introducing fluorinated acetophenone moieties into larger molecular structures, facilitating research in medicinal chemistry and materials science.

IUPAC
ω-Bromo-4-fluoroacetophenone,4-Fluorophenacyl bromide
Synonyms
4-Fluorophenacyl bromideω-Bromo-4-fluoroacetophenone
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2-Bromo-4′-fluoroacetophenone (FC6H4COCH2Br) — chemical structure, CAS 403-29-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Bioactive Small MoleculesBuilding BlocksC7 to C8C7-C8Carbonyl CompoundsCell BiologyChemical SynthesisFluorinated Building BlocksKetonesOrganic Building Blocks
01 /Applications

Pharmaceutical Intermediate

Utilised in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its structure allows for further functionalisation in the development of complex therapeutic agents.

Agrochemical Development

Serves as a building block for novel pesticides, herbicides, and fungicides. The incorporation of fluorine can enhance the biological activity and stability of agrochemical compounds.

Organic Synthesis Reagent

A versatile reagent for introducing the 4-fluorophenacyl group into various organic molecules. Employed in academic and industrial research laboratories for custom synthesis projects.

Material Science

Investigated for its potential in the development of new materials with specific electronic or optical properties, owing to its fluorinated aromatic structure.

02 /Properties
Molecular weight217.04
Linear formulaFC6H4COCH2Br
Assay97%
Boiling point150 °C/12 mmHg(lit.)
Melting point47-49 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Flash point113 °C / 235.4 °F
Transport (UN / ADR)UN 3261 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
403-29-2
MDL number
MFCD00040830
PubChem substance
24864281
05 /Additional specifications
Gene Informationhuman ... PTPN6(5777)
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is 2-Bromo-4′-fluoroacetophenone used for?

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2-Bromo-4′-fluoroacetophenone (CAS 403-29-2) is primarily used as an intermediate in organic synthesis, particularly for developing pharmaceuticals, agrochemicals, and materials science applications.

What is the CAS number and formula for 2-Bromo-4′-fluoroacetophenone?

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The CAS number is 403-29-2 and the linear formula is FC <sub>6</sub> H <sub>4</sub> COCH <sub>2</sub> Br.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Bromo-4′-fluoroacetophenone with an assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.

How should 2-Bromo-4′-fluoroacetophenone be handled?

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2-Bromo-4′-fluoroacetophenone is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment including eyeshields, face shields, chemical-resistant gloves, and respiratory protection (e.g., N100 respirator) must be used. Handle only in a well-ventilated area.

How is 2-Bromo-4′-fluoroacetophenone packed, shipped, and exported?

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This compound is packed according to stringent international safety standards for hazardous materials, including UN 3261 classification. We are experienced exporters and can provide necessary documentation for global shipment.

How can I request a sample or quote for 2-Bromo-4′-fluoroacetophenone?

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Please contact our sales team directly via email or phone to request a sample or a quotation. Provide your specific requirements and shipping details for prompt processing.

Need 2-Bromo-4′-fluoroacetophenone in a specific grade or volume?