3-Fluoro-4-methoxybenzenesulfonyl chloride
3-Fluoro-4-methoxybenzenesulfonyl chloride (CAS 67475-55-2) is a fluorinated organic building block with the empirical formula C7H6ClFO3S and a molecular weight of 224.64 g/mol. This compound serves as a valuable intermediate in organic synthesis, particularly in the preparation of complex molecules within the pharmaceutical and agrochemical industries. Its sulfonyl chloride functionality allows for versatile reactions, making it a key reagent for introducing the 3-fluoro-4-methoxyphenylsulfonyl moiety into target structures.

Pharmaceutical Synthesis
Used as a building block in the synthesis of active pharmaceutical ingredients (APIs). The specific fluorinated and methoxy-substituted phenylsulfonyl group can impart desirable pharmacokinetic or pharmacodynamic properties to drug candidates.
Agrochemical Development
Can be employed in the development of novel pesticides, herbicides, or fungicides. The introduction of fluorinated aromatic systems is a common strategy to enhance the efficacy and stability of agrochemical compounds.
Materials Science
Potentially utilised in the synthesis of specialised polymers or functional materials where the electronic or physical properties conferred by the fluorinated aromatic ring are advantageous.
Research and Development
Serves as a versatile reagent in academic and industrial research laboratories for exploring new chemical reactions and synthesising novel organic molecules.
| Molecular weight | 224.64 |
|---|---|
| Empirical formula | C7H6ClFO3S |
| Assay | 97% |
| Melting point | 77-81 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-4-methoxybenzenesulfonyl chloride used for?
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3-Fluoro-4-methoxybenzenesulfonyl chloride (CAS 67475-55-2) is primarily used as an intermediate in organic synthesis, particularly for creating complex molecules in pharmaceutical and agrochemical research and development.
What is the CAS number and molecular formula?
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The CAS number for 3-Fluoro-4-methoxybenzenesulfonyl chloride is 67475-55-2, and its empirical formula is C7H6ClFO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-4-methoxybenzenesulfonyl chloride with a purity of 97%. We do not represent this product as USP, BP, EP or any other pharmacopoeia grade unless explicitly stated.
How should 3-Fluoro-4-methoxybenzenesulfonyl chloride be handled safely?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handling requires stringent safety measures including wearing appropriate personal protective equipment such as eyeshields, face shields, gloves, and respiratory protection (e.g., N100 or P3 filter cartridges). Always refer to the Safety Data Sheet (SDS) before use.
How is this chemical shipped and exported?
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3-Fluoro-4-methoxybenzenesulfonyl chloride is shipped and exported according to international regulations for hazardous materials, classified under UN 3261, Class 8, Packing Group II.
How can I request a sample or a quote for 3-Fluoro-4-methoxybenzenesulfonyl chloride?
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You can request a sample or a quote by contacting our sales team directly via the website or by calling our customer service number. Please reference the product name and CAS number.
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