Naftopidil hydrochloride hydrate
Naftopidil hydrochloride hydrate, CAS 57149-07-2 (free base), is a chemical compound with the empirical formula C24H28N2O3 · xHCl · yH2O. This white solid, with a molecular weight of 392.49 g/mol (anhydrous free base), functions as an alpha-adrenergic antagonist. It is primarily utilized in research settings, particularly in studies related to cell signaling, neuroscience, and the development of treatments for conditions involving adrenergic receptors.
- IUPAC
- 4-(2-Methoxyphenyl)-α-[(1-naphthalenyloxy)methyl]-1-piperazineethanol hydrochloride hydrate,KT-611
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Adrenergic Receptor Research
Naftopidil hydrochloride hydrate serves as a valuable tool in pharmacological research, specifically for investigating the role of alpha-1 adrenergic receptors (ADRA1A, ADRA1B, ADRA1D) in various physiological processes. Its antagonistic properties allow researchers to probe receptor function and signaling pathways.
Neuroscience and Cell Biology Studies
This compound is employed in studies focused on neuroscience and cell biology, contributing to a better understanding of neurotransmission and cellular responses. Its application aids in dissecting complex biological mechanisms at the cellular level.
GPCR Modulator Research
As a modulator of G protein-coupled receptors (GPCRs), Naftopidil hydrochloride hydrate is utilized in research exploring GPCR function and drug discovery. It aids in the study of membrane protein biology and related signaling cascades.
| Molecular weight | 392.49 (anhydrous free base basis) |
|---|---|
| Empirical formula | C24H28N2O3 · xHCl · yH2O |
| Form | solid |
| Colour | white |
| Solubility | methanol: >10 mg/mLH2O: insoluble |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Naftopidil hydrochloride hydrate used for?
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Naftopidil hydrochloride hydrate is primarily used in research as an alpha-adrenergic antagonist for studies in neuroscience, cell signaling, and GPCR modulation. Its CAS number is 57149-07-2 (free base) and its empirical formula is C24H28N2O3 · xHCl · yH2O.
What is the CAS number and formula for Naftopidil hydrochloride hydrate?
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The CAS number for the free base of Naftopidil hydrochloride hydrate is 57149-07-2. The empirical formula is C24H28N2O3 · xHCl · yH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research purposes. The specific assay and grade are detailed in the product specifications. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Naftopidil hydrochloride hydrate?
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For safe handling, it is recommended to use eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The product has a WGK Germany rating of 3 and RTECS number TL9336500.
How is Naftopidil hydrochloride hydrate packaged and shipped?
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Naftopidil hydrochloride hydrate is typically supplied as a white solid. For specific packaging and shipping details relevant to your region, please contact our sales team. TSS is a global supplier and exporter of fine chemicals.
How can I request a sample or quote for Naftopidil hydrochloride hydrate?
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To request a sample or a quote, please contact the Tech Serve Solutions sales department through our website or by phone. Our team will be happy to assist you with your inquiry.
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