Nafcillin sodium salt monohydrate
Nafcillin sodium salt monohydrate (CAS: 7177-50-6) is a narrow-spectrum β-lactam antibiotic with the molecular formula C21H21N2O5SNa · H2O. It is primarily employed to combat infections caused by Gram-positive bacteria, particularly penicillin-resistant <i>Staphylococci</i>. This compound is also utilised in research for studying penicillin-binding proteins (PBPs) and understanding methicillin resistance mechanisms in <i>Staphylococcus aureus</i>.
- IUPAC
- 6-(2-Ethoxy-1-naphthamido)penicillin
Treatment of Bacterial Infections
Nafcillin sodium salt monohydrate is indicated for treating infections caused by Gram-positive bacteria, specifically <i>Staphylococci</i> species that exhibit resistance to other penicillins. Its narrow-spectrum activity makes it effective against susceptible strains.
Research in Microbiology
This compound serves as a valuable tool in scientific research, particularly for the investigation of penicillin-binding proteins (PBPs). It aids in understanding the mechanisms of antibiotic resistance, such as heterogeneous expression of methicillin resistance in <i>Staphylococcus aureus</i>.
Potential Therapy for Meningitis
Nafcillin sodium has been explored as a potential therapeutic agent for managing meningitis caused by <i>Staphylococcus aureus</i>, highlighting its application in more complex infectious disease scenarios.
| Molecular weight | 454.47 |
|---|---|
| Linear formula | C21H21N2O5SNa · H2O |
| Storage temperature | 2-8°C |
| Application | Nafcillin sodium is a narrow-spectrum β-lactam antibiotic. It is used to treat infections caused by Gram-positive bacteria, in particular, species of Staphylococci that are resistant to other penicillins. Nafcillin is used to study penicillin binding proteins (PBPs). It has been used to study penicillin-binding proteins 2a and heterogeneous expression of methicillin resistance in Staphylococcus aureus 1. It is a potential therapy of meningitis due to Staphylococcus aureus.2. |
Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nafcillin sodium salt monohydrate used for?
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Nafcillin sodium salt monohydrate is used to treat infections caused by Gram-positive bacteria, particularly penicillin-resistant <i>Staphylococci</i>, and in research for studying penicillin-binding proteins.
What are the CAS number and chemical formula?
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The CAS number for Nafcillin sodium salt monohydrate is 7177-50-6, and its chemical formula is C21H21N2O5SNa · H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nafcillin sodium salt monohydrate typically as a research or technical grade chemical. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should Nafcillin sodium salt monohydrate be handled safely?
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Handling Nafcillin sodium salt monohydrate requires caution due to potential skin and respiratory irritation and sensitisation. Use appropriate personal protective equipment including a dust mask (N95 recommended), eyeshields, face shield, and gloves. Ensure adequate ventilation and avoid dust formation. Refer to the Safety Data Sheet for detailed handling procedures.
Is Nafcillin sodium salt monohydrate suitable for therapeutic use?
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While Nafcillin sodium is an antibiotic used in medicine, the product supplied by Tech Serve Solutions is intended for laboratory research and development purposes only. It is not intended for human or veterinary use unless specified as pharmacopoeia grade, which is not standard for this catalogue item.
How is Nafcillin sodium salt monohydrate shipped and exported?
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Nafcillin sodium salt monohydrate is carefully packaged and can be shipped and exported globally by Tech Serve Solutions, adhering to all relevant shipping and customs regulations for chemical substances.
How can I request a quote or sample?
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To request a quote or a sample of Nafcillin sodium salt monohydrate, please visit the product page on our website and use the 'Request Quote' or 'Request Sample' functionality, or contact our sales team directly.
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