Nalidixic acid sodium salt
Nalidixic acid sodium salt (CAS: 3374-05-8) is a sodium salt derivative of nalidixic acid with the empirical formula C12H11N2NaO3 and a molecular weight of 254.22 g/mol. This compound functions as an antibacterial agent, primarily by interfering with DNA synthesis in susceptible bacteria. It is supplied by TSS with an assay of ≥95% and contains ≤7% water, typically stored under refrigerated conditions (2-8°C).
- IUPAC
- 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt

Antibacterial Agent
Nalidixic acid sodium salt acts as a broad-spectrum antibacterial agent. It functions by inhibiting bacterial DNA gyrase, an enzyme essential for DNA replication, transcription, repair, and recombination.
Research Chemical
This compound serves as a valuable reagent in biochemical and cell biology research. Its specific mechanism of action, interfering with DNA synthesis, makes it useful for studying bacterial genetics and antimicrobial resistance.
Intermediate in Synthesis
As a derivative of nalidixic acid, the sodium salt can potentially be used as an intermediate in the synthesis of other related compounds or modified pharmaceutical agents, though specific applications are not detailed.
| Molecular weight | 254.22 |
|---|---|
| Empirical formula | C12H11N2NaO3 |
| Assay | ≥95% (NT) |
| Solubility | H2O: soluble50 mg/mL, clear, faintly yellow |
| Storage temperature | 2-8°C |
| Impurities tested | ≤7% water |


Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 42/43 |
| Safety statements (S) | 22-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nalidixic acid sodium salt used for?
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Nalidixic acid sodium salt is primarily used as an antibacterial agent that interferes with bacterial DNA synthesis and as a research chemical in biochemical and cell biology studies.
What are the CAS number and formula for Nalidixic acid sodium salt?
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The CAS number for Nalidixic acid sodium salt is 3374-05-8, and its empirical formula is C12H11N2NaO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nalidixic acid sodium salt with an assay of ≥95% and not more than 7% water. We do not represent this product as USP, BP, or EP grade.
How should Nalidixic acid sodium salt be handled safely?
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Nalidixic acid sodium salt is classified as dangerous. It is harmful if swallowed (H302), may cause an allergic skin reaction (H317), and may cause allergy or asthma symptoms or breathing difficulties if inhaled (H334). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shield, and gloves, should be used. Handle in a well-ventilated area or fume hood.
Is Nalidixic acid sodium salt a controlled substance?
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The provided data does not indicate that Nalidixic acid sodium salt is a controlled substance.
How is Nalidixic acid sodium salt packed and shipped?
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Nalidixic acid sodium salt is typically stored at 2-8°C. TSS ensures proper packaging and adherence to regulations for global export of this chemical.
How can I request a quote or sample?
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To request a quote or sample of Nalidixic acid sodium salt, please contact our sales department through the website or via email.
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