SB-215505

CAS 162100-15-4C19H16N3OClBiochemicals & Reagents

SB-215505 (CAS: 162100-15-4) is a chemical compound with the formula C19H16N3OCl and a molecular weight of 337.80 g/mol. This off-white solid is primarily used as a research tool in cell biology and neuroscience, specifically for studying G-protein coupled receptors (GPCRs). Its applications lie in investigating neurotransmission and related cellular signalling pathways, serving as a valuable reagent for scientific research and drug discovery.

IUPAC: 6-Chloro-5-methyl-1-5-quinolycarbamoyl-indoline

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SB-215505 (C19H16N3OCl) — chemical structure, CAS 162100-15-4; Life Science, fine chemical supplied by Tech Serve Solutions

AntagonistsBioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesGlaxoSmithKlineNeuroscienceNeurotransmission

01 /Applications

Neuroscience Research

SB-215505 acts as an antagonist, making it useful for studying the roles of specific receptors in neurotransmission and neuronal signalling within the central nervous system.

GPCR Modulator Studies

As a modulator of GPCRs, this compound aids in understanding the complex signalling cascades initiated by these receptors, crucial for various physiological processes.

Drug Discovery and Development

Its function as a drug candidate or approved therapeutic tool makes SB-215505 a significant molecule for early-stage research in developing novel therapeutics targeting neurological disorders.

Cellular Signalling Investigations

This chemical is employed to investigate intracellular communication pathways, particularly those involving membrane proteins and their downstream effects.

02 /Properties

Molecular weight	337.80
Empirical formula	C19H16N3OCl
Assay	>98% (HPLC)
Form	solid
Colour	off-white
Solubility	DMSO: soluble ~11 mg/mL at 60 °CH2O: insoluble
Storage temperature	2-8°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

162100-15-4

MDL number

MFCD05664741

05 /Additional specifications

Gene Information	human ... HTR2B(3357)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is SB-215505 used for?

SB-215505 is used in scientific research, particularly in neuroscience and cell biology, as a G-protein coupled receptor (GPCR) antagonist and a tool for studying neurotransmission and cellular signalling pathways. It has also been investigated as an approved therapeutic or drug candidate.

What is the CAS number and chemical formula for SB-215505?

The CAS number for SB-215505 is 162100-15-4, and its empirical formula is C19H16N3OCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies SB-215505 with a purity of >98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

What are the safety and handling recommendations for SB-215505?

Handle SB-215505 with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It has a WGK rating of 3 in Germany, indicating a high hazard level.

How is SB-215505 shipped and exported?

SB-215505 is stored at 2-8°C. Tech Serve Solutions exports chemicals globally, adhering to all necessary regulations for safe and compliant international shipping.