SBFI-AM
SBFI-AM (CAS: 129423-53-6; C56H58N2O23) is a cell-permeant, sodium-selective fluorescent indicator. This bioactive small molecule is instrumental in the study of cellular processes involving sodium ion dynamics. Its primary application lies in visualising and quantifying intracellular sodium concentrations in various cell types, aiding research in cell biology, signalling, and neuroscience. With a molecular weight of 1127.06 g/mol, SBFI-AM offers researchers a reliable tool for investigating ion channel function and membrane transport.
- IUPAC
- Sodium indicator SBFI-AM,Sodium-binding benzofuran isophthalate-AM
- Synonyms
- Sodium-binding benzofuran isophthalate-AM

Intracellular Sodium Measurement
SBFI-AM serves as a precise fluorescent probe for measuring intracellular sodium ion (Na+) concentrations in living cells. Its selectivity allows for accurate monitoring of sodium fluxes across cell membranes, crucial for understanding cellular homeostasis and signalling.
Ion Channel and Transporter Research
This indicator is widely used to study the activity of sodium channels and transporters. Researchers employ SBFI-AM to investigate how these proteins modulate cellular sodium levels in response to various stimuli or pharmacological interventions.
Cell Signaling and Neuroscience Studies
In neuroscience, SBFI-AM aids in understanding the role of sodium ions in neuronal excitability, synaptic transmission, and the aetiology of neurological disorders. Its application extends to studying calcium-sodium exchange mechanisms in excitable cells.
Cell Biology Investigations
SBFI-AM is a valuable tool for general cell biology research, enabling the examination of sodium's involvement in diverse cellular functions, including cell volume regulation, pH balance, and energy metabolism.
| Molecular weight | 1127.06 |
|---|---|
| Empirical formula | C56H58N2O23 |
| Storage temperature | −20°C |
| Application | Cell permeant sodium selective fluorescent indicator |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SBFI-AM used for?
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SBFI-AM (CAS: 129423-53-6) is a cell-permeant, sodium-selective fluorescent indicator used to measure intracellular sodium ion concentrations in biological research, particularly in cell biology, neuroscience, and the study of ion channels and transporters.
What are the CAS number and molecular formula for SBFI-AM?
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The CAS number for SBFI-AM is 129423-53-6, and its molecular formula is C56H58N2O23.
What grade and purity does Tech Serve Solutions supply for SBFI-AM?
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Tech Serve Solutions supplies SBFI-AM at a research grade. The specific purity details can be found on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the primary safety considerations when handling SBFI-AM?
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SBFI-AM requires the use of personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It carries a WGK Germany rating of 3, indicating a high hazard level.
How is SBFI-AM packed, shipped, and exported?
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SBFI-AM is typically stored at -20°C. Tech Serve Solutions ensures compliant packing and international export procedures for all its chemical products, adhering to global shipping regulations.
How can I request a sample or quote for SBFI-AM?
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To request a sample or obtain a quote for SBFI-AM, please contact the Tech Serve Solutions sales team via the website or directly through the provided contact channels.
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