Naltrexone hydrochloride
Naltrexone hydrochloride (CAS: 16676-29-2), with the molecular formula C20H23NO4 · HCl and a molecular weight of 377.86 g/mol, is a key opioid antagonist. It acts primarily by blocking the effects of exogenous opioids and reducing the rewarding effects of alcohol and opiates. This compound is extensively researched for its potential in managing opioid and alcohol dependence.
Opioid Receptor Antagonism
Naltrexone hydrochloride serves as a potent antagonist at mu, kappa, and delta opioid receptors. This property is foundational for its use in blocking the euphoric and sedative effects of opioid drugs.
Alcohol Dependence Treatment
It is utilised to reduce cravings and the rewarding effects associated with alcohol consumption. By modulating neurotransmitter systems, it aids in maintaining abstinence in individuals recovering from alcohol use disorder.
Research Tool in Neuroscience
As a well-characterised opioid antagonist, it is employed in neurobiological research to investigate the roles of opioid receptors in various physiological and behavioural processes.
GPCR Research
Naltrexone hydrochloride is valuable in studies involving G protein-coupled receptors (GPCRs), particularly opioid receptors, offering insights into their signalling pathways and modulation.
| Molecular weight | 377.86 |
|---|---|
| Empirical formula | C20H23NO4 · HCl |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... OPRD1(4985), OPRK1(4986), OPRM1(4988), OPRS1(10280) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Naltrexone hydrochloride used for?
+
Naltrexone hydrochloride is primarily used to manage opioid and alcohol dependence by blocking the effects of opioids and reducing alcohol cravings. It is also used as a research tool in neuroscience and GPCR studies.
What is the CAS number and formula for Naltrexone hydrochloride?
+
The CAS number for Naltrexone hydrochloride is 16676-29-2, and its molecular formula is C20H23NO4 · HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Naltrexone hydrochloride as a research-grade chemical. The exact purity is available on the Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should Naltrexone hydrochloride be handled and stored?
+
Naltrexone hydrochloride is harmful if swallowed (H302). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Store at 2-8°C.
Is Naltrexone hydrochloride a controlled substance?
+
While Naltrexone hydrochloride is used to treat dependence on controlled substances, it is not typically scheduled as a controlled substance itself. However, regulations can vary by jurisdiction.
How can I request a quote or sample for Naltrexone hydrochloride?
+
To request a quote or sample, please contact our sales team via the website or direct email, specifying the product name and CAS number (16676-29-2).
Is Naltrexone hydrochloride available for export?
+
Yes, Tech Serve Solutions is a global supplier and exporter of Naltrexone hydrochloride, adhering to all relevant international shipping and customs regulations.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis