Naphthofluorescein
Naphthofluorescein (CAS: 61419-02-1, C28H16O5) is a fluorescent compound with a molecular weight of 432.42 g/mol. This versatile chemical exhibits fluorescent properties and is recognised for its utility as a pH indicator. Its solubility in DMF, DMSO, and aqueous solutions at pH 8 and above makes it adaptable for various laboratory applications.

Fluorescent pH Indicator
Naphthofluorescein functions as a fluorescent indicator for pH measurements, exhibiting specific excitation and emission wavelengths. Its fluorescence is useful in a variety of aqueous and solvent-based systems where pH monitoring is critical.
Fluorescence-Based Detection
The compound's fluorescent characteristics make it suitable for applications requiring sensitive detection methods. It can be employed in various analytical techniques where a fluorescent signal is advantageous.
Biochemical and Reagent Use
As a biochemical reagent, Naphthofluorescein is utilised in laboratory research and diagnostics. Its properties lend themselves to investigations in cell biology and analytical chemistry.
| Molecular weight | 432.42 |
|---|---|
| Empirical formula | C28H16O5 |
| Solubility | DMF: solubleDMSO: solubleH2O: soluble (pH ≥ 8) |
| Application | suitable as pH-indicator |
| Suitability | suitable for fluorescence |
| Melting point | 189 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Pka  | 7.6 |
|---|---|
| Fluorescence | λex 594 nm; λem 663 nm in 0.1 M Tris pH 9.0 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Naphthofluorescein used for?
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Naphthofluorescein is primarily used as a fluorescent pH indicator and for fluorescence-based detection in laboratory and research settings. It is also employed as a biochemical reagent.
What are the CAS number and formula for Naphthofluorescein?
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The CAS number for Naphthofluorescein is 61419-02-1, and its empirical formula (Hill notation) is C28H16O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Naphthofluorescein as a technical/research grade chemical. We do not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for Naphthofluorescein?
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Naphthofluorescein is labelled with a GHS07 symbol and 'Warning' signal word, with hazard statements including H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Recommended personal protective equipment includes a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
How is Naphthofluorescein packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports Naphthofluorescein globally, adhering to all relevant regulations for chemical transport.
How can I request a sample or quote for Naphthofluorescein?
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To request a sample or a quote for Naphthofluorescein, please contact our sales department via the website or your dedicated account manager.
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