Naphazoline hydrochloride
Naphazoline hydrochloride (CAS 550-99-2), with the molecular formula C14H14N2 · HCl and a molecular weight of 246.74 g/mol, is a chemical compound primarily utilised for its vasoconstrictive properties. It acts as an alpha-adrenergic agonist. This compound finds application in formulations designed to alleviate temporary nasal congestion and reduce redness of the eye.
- IUPAC
- 2-(1-Naphthylmethyl)imidazoline hydrochloride
- Synonyms
- 2-(1-Naphthylmethyl)imidazoline hydrochloride

Nasal Decongestant Formulations
Naphazoline hydrochloride is an active ingredient in some over-the-counter nasal sprays. It constricts blood vessels in the nasal mucosa, providing temporary relief from nasal stuffiness.
Ophthalmic Decongestant Solutions
As an alpha-adrenergic agonist, it is used in eye drops to reduce redness and swelling associated with minor eye irritations. It achieves this by narrowing the blood vessels in the conjunctiva.
Research and Development
This compound serves as a reference standard and research tool in pharmacological studies, particularly in areas related to adrenergic receptor activity and cardiovascular research.
| Molecular weight | 246.74 |
|---|---|
| Empirical formula | C14H14N2 · HCl |

Hazard statements
- H300Fatal if swallowed
Precautionary statements
- P264Wash thoroughly after handling
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Naphazoline hydrochloride (CAS 550-99-2) used for?
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Naphazoline hydrochloride (CAS 550-99-2) is primarily used in formulations for nasal decongestion and to reduce eye redness due to its vasoconstrictive properties as an alpha-adrenergic agonist.
What is the CAS number and formula for Naphazoline hydrochloride?
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The CAS number for Naphazoline hydrochloride is 550-99-2 and its molecular formula is C14H14N2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Naphazoline hydrochloride. The specific grade and purity (assay) will be detailed on the Certificate of Analysis for the batch supplied. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should Naphazoline hydrochloride be handled safely?
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Naphazoline hydrochloride is classified as acutely toxic (Danger, H300). Handling requires appropriate personal protective equipment including eyeshields, face shields, gloves, and P2 respirator cartridges. Always consult the Safety Data Sheet (SDS) before use.
Is Naphazoline hydrochloride a controlled substance?
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Based on the provided data, Naphazoline hydrochloride (CAS 550-99-2) is not indicated as a controlled substance. However, regulations can vary by region.
How is Naphazoline hydrochloride packed, shipped, and exported?
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Naphazoline hydrochloride is packed according to industry standards to ensure safe transport and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations, including UN 2811 classification for toxic solids.
How can I request a quote or sample for Naphazoline hydrochloride?
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To request a quote or sample for Naphazoline hydrochloride, please contact our sales department through the website or provide your details via the enquiry form.
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