2-Chloro-N,N-diethylacetamide
2-Chloro-N,N-diethylacetamide (CAS 2315-36-8) is an organic compound with the linear formula ClCH₂CON(C₂H₅)₂ and a molecular weight of 149.62 g/mol. It is a carbonyl compound primarily used as a building block in organic synthesis. Its applications include the preparation of complex molecules such as calixarene derivatives and macrocyclic compounds. Available from Tech Serve Solutions at 97% purity, it serves as a valuable reagent for chemical research and development.
- Synonyms
- ClCH2CON(C2H5)2
Synthesis of Calixarene Derivatives
2-Chloro-N,N-diethylacetamide has been employed in the preparation of various calixarene amides and functionalised calix[4]arenes. These derivatives are investigated for their host-guest chemistry and supramolecular applications.
Macrocycle Synthesis
This compound acts as a key reagent in the synthesis of amide calix[4]pyrrole macrocycles. These macrocycles possess super-extended cavities, making them of interest in supramolecular chemistry research.
Microwave-Assisted Organic Synthesis
2-Chloro-N,N-diethylacetamide has been utilised in microwave-assisted reactions for the efficient synthesis of substituted butanamides, such as 3-cyano-N,N-diethyl-4-(4-methoxyphenyl)-4-oxobutanamide.
| Molecular weight | 149.62 |
|---|---|
| Linear formula | ClCH2CON(C2H5)2 |
| Assay | 97% |
| Boiling point | 148-150 °C/55 mmHg(lit.) |
| Density | 1.089 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.47(lit.) |
| Application | 2-Chloro-N,N-diethylacetamide has been used in:• preparation of calixarene amides1• synthesis of 5-bromo-25,26,27,28-tetrakis[(N,N-diethylaminocarbonyl)-methoxy]calix[4]arene2• synthesis of amide calix[4]pyrrole macrocycles with super-extended cavities3• microwave-assisted organic synthesis of 3-cyano-N,N-diethyl-4-(4-methoxyphenoyl)-4-oxobutanamide4 |
Hazard statements
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H330Fatal if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-N,N-diethylacetamide used for?
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2-Chloro-N,N-diethylacetamide is used as a building block in organic synthesis, particularly for preparing calixarene derivatives, macrocyclic compounds, and other complex organic molecules. It is also employed in microwave-assisted organic synthesis.
What is the CAS number and formula for 2-Chloro-N,N-diethylacetamide?
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The CAS number is 2315-36-8 and the linear formula is ClCH₂CON(C₂H₅)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-N,N-diethylacetamide with a purity of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Chloro-N,N-diethylacetamide be handled safely?
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This compound is classified as Danger, with hazards including being harmful if swallowed, toxic in contact with skin, causes skin irritation, causes serious eye irritation, and toxic if inhaled. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area.
Is 2-Chloro-N,N-diethylacetamide a controlled substance?
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The provided data does not indicate that 2-Chloro-N,N-diethylacetamide is a controlled substance.
How is 2-Chloro-N,N-diethylacetamide packed and shipped?
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2-Chloro-N,N-diethylacetamide is shipped according to UN 2810, Class 6.1, Packing Group III regulations. Packaging details are available upon request.
How can I request a quote or sample?
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Please contact Tech Serve Solutions directly via our website or contact details to request a quote or a sample of 2-Chloro-N,N-diethylacetamide.
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